Faculty and research interests
Molecular mechanisms of DNA rearrangement/recombination reactions
Multinuclear magnetic resonance techniques; metalloproteins/metal homeostasis; Alzheimer's Disease.
Mechanotransduction; X-ray crystallography; Single molecule force spectroscopy; Regulated Intramembrane Proteolysis; Cell signaling assays; Protein labeling
Biomolecular NMR spectroscopy; Protein dynamics; Molecular machineries; Cell signaling; Molecular chaperones; Membrane transporters
Oxygenase mechanisms, metalloproteins, magnetic resonance techniques, kinetics.
Cell adhesion; protein-protein/carbohydrate interactions.
Protein engineering; structural biology; x-ray crystallography; molecular biology.
Muscle molecular dynamics, spectroscopy, and therapeutic discovery.
Structure and dynamics of membrane embedded enzymes. (Division Head)
Structural enzymology: Metal ions & organic co-factors; Human disease: cardiovascular, Alzheimers.
Biological networks that coordinate metabolism and growth.
Diabetes, metabolite sensing and signaling, metabolic enzyme regulation.
Joint Members - From Other Departments
Que, Jr., Lawrence
Active site structures and mechanisms of nonheme iron enzymes; trapping of reactive intermediates, design and synthesis of functional metalloenzyme models and chiral oxidation catalysts; artificial DNA hydolysis agents.
Biophysical Technology Center
Director: Dr. Mike Autry
Optics Manager: Dr. Ji Li
EPR Manager: Dr. Andrew Thompson
Faculty Research Interests