Instrumentation

 

Mass Spectrometers
Features

LTQ Orbitrap Velos*, Thermo Scientific

Linear ion trap and orbital trap MS; ESI and nanoESI source; CID, PQD, HCD, and ETD activation; Eksigent Technologies, LLC Ultra 1D nano-HPLC System and microAS autosampler

Q Exactive*, Thermo Scientific

Orbitrap mass analyzer; S-lens ion source; HCD collision cell; Hyperbolic quadrupole mass filter; Dionex UltiMate 3000 Binary RSLC System.

Orbitrap Fusion™ Tribrid™,  Thermo Scientific  (with Yue Chen Lab)

Orbitrap mass analyzer; EASY-Max NG™ API source ; Quadrupole, Linear Ion Trap and Orbitrap Mass Analyzer; EASY-nLC™ 1000

Autoflex speed MALDI TOF/TOF System*, Bruker

 

MALDI-Time-Of-Flight Mass Spectrometer; MALDI Perpetual ion source; smartbeam-II laser technology; TOF analyzer for linear and reflectron measurements in positive/negative ion mode; MS/MS capability.

TripleTOF 5600+ System®, Sciex  (with Laurie Parker Lab)

TripleTOF 5600+ System with the Accelerator TOF Analyzer; DuoSpray™ ion source combines a TurboIonSpray® probe and an APCI (atmospheric pressure chemical ionization) probe; LINAC® collision cell; Accelerator TOF™ Analyzer.

5500 QTRAP®, Sciex

Triple Quadrupole with Q3 Linear Trap MS, capillary and analytical HPLC; Turbo Ion Spray®, IonSpray, nano-ESI

4000 QTRAP®, Sciex

Triple Quadrupole with Q3 Linear Trap MS; analytical HPLC; Turbo Ion Spray®, nano-Spray II (AB Sciex)

LTQ, Thermo Scientific

Linear Ion Trap MS, ESI, nanoESI, Michrom BioResources Paradigm 2D capLC, DESI (Prosilia, Inc.)

LCT Premier XE ESI-TOF, Waters

ACQUITY UPLC, ESI source

Pegasus 4D GCxGC TOF MS, LECO

Agilent 6890N GC, 7683B Autosampler

LCQ, Thermo Scientific

Electrospray-Ion Trap Mass Spectrometry, SpectraSystem P4000 HPLC, AS3000 Autosampler, UV6000L diode array detector; ESI, APCI

Sample Prep/Off-line Separation
Features

Shimadzu Prominence

Off-line peptide fractionation (e.g., RP C18 at high pH, ERLIC, SCX) with fraction collector

Barocycler® NEP2320

Pressure Biosciences Inc Performs cell lysis and enzymatic digestion under high pressure in small volumes and short time intervals

Typhoon 8610 Scanner

Gel Scanner