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Wackett Lab

Research Overview

The Wackett laboratory studies microbial enzymes and pathways for biocatalysis and biodegradation and helped build the Biocatalysis/Biodegradation Database.

Biodegradation
  • Atrazine – Biocatalyst encapsulation and water treatment
  • Cyanuric acid – Removal from swimming pool water
  • Emerging pollutants - Bioremediation of personal care products
  • Aromatic hydrocarbons – Modeling and mechanisms
Biocatalysis
  • Hydrocarbon biosynthesis – Enzyme structure and mechanisms
  • Enzyme-based sensors for detecting toxicants
  • Predicting biocatalytic potential of enzymes and microbes

News Highlights

Cyanuric acid hydrolase evolution – Seffernick and Wackett 2016, A primordial enzyme, Appl Environ Microbiol 82: 1638-1645

Polycyclic Aromatic Hydrocarbon (PAH) oxidation – Sakkos, J.K., et al 2016,  Hydrocarbon oxidation by immobilized cells. Biotechnol. Bioeng. 113: 3513-521

Bioremediation startup founded – Minnepura Technologies, Inc.

Minnepura in the news - Startups out of the University of Minnesota

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