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Publications

1. Wackett, L.P. and D.T. Gibson (1982) The metabolism of xenobiotic com¬pounds by enzymes in cell extracts of the fungus Cunninghamella elegans. Biochem. J. 205:117-122

2. Wackett, L.P. and D.T. Gibson (1983) Rapid method for detection and quan¬titation of hydroxylated intermediates produced by microorganisms. Appl. Environ. Microbiol. 45:1144-1147.

3. Ensley, B.D., M.B. Mann, T.D. Osslund, M.J. Simon, L.P. Wackett, and D.T. Gibson (1983) Expression of naphthalene oxidation genes in Escherichia coli results in the biosynthesis of indigo. Science 222:167-169.

4. Subramanian, V., T-N. Liu, W-K. Yeh, C. Serdar, L.P. Wackett, and D.T. Gibson (1985) Purification and properties of ferredoxinTOL: A component of toluene dioxyge¬nase from Pseudomonas putida F1. J. Biol. Chem. 260:2355-2363.

5. Wackett, L.P., S.L. Shames, C.P. Venditti, and C.T. Walsh (1987) Bacterial C-P lyase: Products, rates, and regulation of phosphonic and phosphinic acid metabolism. J. Bacteriol. 169:710-717.

6. Wackett, L.P., E.A. Hartwieg, J.A. King, W.H. Orme-Johnson and C.T. Walsh (1987) Electron microscopy of key nickel-containing enzymes: Methyl reduc¬tase and F420-reducing hydrogenase. J. Bacteriol. 169:718-727.

7. Wackett, L.P., B.L. Wanner, C.P. Venditti, and C.T. Walsh (1987) Involvement of the phosphate regulon and the psiD locus in the C-P lyase activity of Escherichia coli K-12. J. Bacteriol. 169:1753-1756.

8. Shames, S.L., L.P. Wackett, M.S. LeBarge, R.L. Kuczkowski and C.T. Walsh (1987) Fragmentative and stereochemical isomerization probes for homolytic carbon to phos¬phorus bond scission catalyzed by bacterial C-P lyase. Bioorganic Chemistry 15:366-373.

9. Wackett, L.P., J.F. Honek, T.P. Begley, V. Wallace, W.H. Orme-Johnson and C.T. Walsh (1987) Substrate analogues as mechanistic probes of methyl-S-coenzyme M reductase. Biochemistry 26:6012-6018.

10. Wackett, L.P., L.D. Kwart, and D.T. Gibson (1988) Benzylic monooxygenation catalyzed by toluene dioxygenase from Pseudomonas putida. Biochemistry 27:1360-1367.

11. Wackett, L.P., J.F. Honek, T.P. Begley, S.L. Shames, E.C. Niederhoffer, R.P.Hausinger, W.H. Orme-Johnson, and C.T. Walsh (1988) Methyl-S-coenzyme M reductase: A nickel-dependent enzyme catalyzing the terminas redox step in methane biogenesis. In (J. Lancaster, ed.) Bioinorganic Chemistry of Nickel VCH, Florida, p. 249-274.

12. Bastian, N.R., D.A. Wink, L.P. Wackett, D.J. Livingston, L.M. Jordan, J. Fox, W.H. Orme-Johnson, and C.T. Walsh (1988) Hydrogenases of Methanobacterium thermoautotrophicum strain vH. In (J. Lancaster, ed.) Bioinorganic Chemistry of Nickel VCH, Florida, p. 227-247.

13. Wackett, L. P. and D. T. Gibson (1988) Degradation of trichloroethylene by toluene dioxygenase in whole cell studies with Pseudomonas putida F1. Appl. Environ. Microbiol. 54:1703-1708.

14. Scholtz, R., L. P. Wackett, C. Egli, A. M. Cook and T. Leisinger (1988) Dichloromethane dehalogenase with improved catalytic activity isolated from a fast-growing dichloromethane-utilizing bacterium. J. Bacteriol. 170:5698-5704.

15. Wackett, L. P. and S. R. Householder (1989) Toxicity of trichloroethylene to Pseudomonas putida F1 is mediated by toluene dioxygenase. Appl. Environ. Microbiol. 55:2723-2725.

16. Wackett, L. P., G. Brusseau, S. Householder and R. S. Hanson (1989) Survey of microbial oxygenases: Trichloroethylene degradation by propane-oxidizing bacteria. Appl. Environ. Microbiol. 55:2960-2964.

17. Tsien, H.-C., G. A. Brusseau, R. S. Hanson and L. P. Wackett (1989) Biodegradation of trichloroethylene by Methylosinus trichosporium OB3b. Appl. Environ. Microbiol. 55:3155-3161.

18. Zylstra, G. J., L. P. Wackett and D. T. Gibson (1989) Degradation of trichloroethylene by Pseudomonas putida F1 toluene dioxygenase cloned in Escherichia coli. Appl. Environ. Microbiol. 55:3162-3166.

19. Wackett, L. P. W. H. Orme-Johnson and C. T. Walsh (1989) Transition metal enzymes in bacterial metabolism. In (T. Beveridge and R. J. Doyle, ed.) Metal Ions and Bacteria, p. 165-206.

20. Fox, B., J. G. Borneman, L. P. Wackett, and J. D. Lipscomb (1990) Haloalkene oxidation by the soluble methane monooxygenase from Methylosinus trichosporium OB3b: Mechanistic and environmental implications. Biochemistry 29:6419-6427.

21. Hanson, R. S., H. C. Tsien, K. Tsuji, G. A. Brusseau, and L. P. Wackett (1990) Biodegradation of low-molecular weight halogenated hydrocarbons by methanotrophic bacteria. FEMS Microbiol. Rev. 87:273-278.

22. Brusseau, G. A., R. S. Hanson and L. P. Wackett (1990) Optimization of trichloroethylene oxidation by methanotrophs using a colorimetric assay for soluble methane monooxygenase. Biodegradation 1:19-29.

23. William, M. G., P. E. Olson, K. J. Tautvydas, R. M. Bitner, R. A. Mader and L. P. Wackett (1990) The application of toluene dioxygenase in the synthesis of acetylene-terminated resins. Appl. Microbiol. Biotechnol. 34:316-321.

24. Wackett, L. P. (1990) Toluene Dioxygenase. In (M. E. Lidstrom, ed.) Methods in Enzymology, Vol. 188, p. 39-45.

25. Gantzer, C. J. and L. P. Wackett (1991) Reductive dechlorination catalyzed by bacterial transition-metal coenzymes. Environ. Sci. Tech. 25:715-722.

26. Newman, L. and L. P. Wackett (1991) Production and fate of trichloroacetaldehyde (chloral hydrate) in methanotrophic cultures. Appl. Environ. Microbiol. 57:2399-2402.

27. Wackett, L. P. (1991) Dehalogenase reactions catalyzed by bacteria. In (A. M. Martin, ed.) Biological Degradation of Wastes, p. 187-205.

28. Tsien, H. C., G. A. Brusseau, L. P. Wackett and R. S. Hanson (1991) Microbial degradation of low molecular weight halogenated hydrocarbons. In Coal and Gas Biotechnology, Institute for Gas Technology, Chicago.

29. Hanson, R. S., H. C. Tsien, K. Tsuji, G. A. Brusseau and L. P. Wackett (1991) Biodegradation of low molecular weight halogenated hydrocarbons by methanotrophic bacteria. In (J. R. Andreesen and B. Bowien, eds.) Proceedings of the 6th International C-1 Symposium.

30. Schanke, C. and L. P. Wackett. (1992) Transition-metal coenzymes mimic environmental reductive elimination reactions of polychlorinated ethanes. Environ. Sci. Tech. 26:830-833.

31. Li, S. & L.P. Wackett (1992) Trichloroethylene oxidation by toluene dioxygenase. Biochem. Biophys. Res. Comm. 58:2820-2826.

32. Olson, P.E., B. Qi, L. Que & L.P. Wackett (1992). Diverse Arthrobacter strains biosynthesize a unique managanese-containing dioxygenase for catabolism of aromatic acids. Appl. Environ. Microbiol. 58:2820-2826.

33. Blocki, F.A., P.M. Schlievert & L.P. Wackett (1992) Rat liver protein linking chemical and immunological detoxification systems. Nature 360:269-270.

34. Wackett, L.P., M.S.P. Logan, F.A. Blocki & C. Baoli (1992) A mechanistic perspective on bacterial metabolism of chlorinated methanes. Biodegradation 3:19-36.

35. Wackett, L. P. and C. A. Schanke (1992) Mechanisms of reductive dehalogenation by transition metal cofactors found in anaerobic bacteria. In (H. Sigel, ed.) Metal Ions in Biological Systems, p. 329-356.

36. Wackett, L. P. (1992) Dehalogenation of organohalide pollutants by bacterial enzymes and coenzymes. In (A. E. Martell, ed.) Applications of Enzyme Biotechnology, Plenum Press, New York, p. 191-200.

37. Logan, M.S., L.M. Newman, C.A. Schanke, and L.P. Wackett (1993) Cosubstrate effects in reductive dehalogenation by Pseudomonas putida G786 expressing cytochrome P-450CAM. Biodegradation 4:39-50.

38. Mandelbaum, R.T., L.P. Wackett and D.L. Allan (1993) Mineralization of the s-triazine ring of atrazine by stable bacterial mixed cultures. Appl. Environ. Microbiol. 59:1695-1701.

39. Li, S. and L.P. Wackett (1993) Reductive dehalogenation by cytochrome P450CAM: Substrate binding and catalysis. Biochemistry 32:9355-9361.

40. Mandelbaum, R.T., L.P. Wackett and D.L. Allan (1993) Soil bacteria rapidly hydrolyze atrazine to hydroxyatrazine. Environ. Sci. Technol. 27:1943-1946.

41. Blocki, F.A., L.B.M. Ellis and L.P. Wackett (1993) MIF proteins are theta glutathione S-transferase homologs. Protein Science 2:2095-2102.

42. Logan, M.S.P., F.A. Blocki, K.J. Stimpfl and L.P. Wackett (1993) Haloacetonitriles are low KI inhibitors of bacterial dichloromethane dehalogenases. Biochem. Biophys. Res. Comm. 197:853-858.

43. Wackett, L.P., M.J. Sadowsky, L.M. Newman, H-G. Hur and S. Li (1994) Metabolism of polyhalogenated compounds by a genetically engineered bacterium. Nature 368:627-629.

44. Blocki, F.A., M.S.P. Logan, C. Baoli and L.P. Wackett (1994) Reaction of rat liver glutathione S-transferases and bacterial dichloromethane dehalogenase with dihalomethanes. J. Biol. Chem. 269:8826-8830.

45. Lefever, M.R. and L.P. Wackett (1994) Oxidation of low molecular weight chloroalkanes by cytochrome P450CAM. Biochem. Biophys. Res. Comm. 201:373-378.

46. Wackett, L.P. (1994) Dehalogenation in environmental biotechnology. Curr. Op. Biotech. 5:260-265.

47. Hur, H-G., M.J. Sadowsky and L.P. Wackett (1994) Metabolism of chlorofluorocarbons and polybrominated compounds by Pseudomonas putida G786 (pHG-2) via an engineered metabolic pathway. Appl. Environ. Microbiol. 60:4148-4154.

48. Mandelbaum, R.T., D.A. Allan and L.P. Wackett (1995) Isolation and characterization of a Pseudomonas sp. that mineralizes the s-triazine herbicide atrazine. Appl. Environ. Microbiol. 61:1451-1457.

49. Boldt, Y.R., M.J. Sadowsky, L.B.M. Ellis, L. Que, Jr. and L.P. Wackett (1995) A manganese-dependent dioxygenase from Arthrobacter globiformis strain CM-2 belongs to the major extradiol dioxygenase family. J. Bacteriol. 177:1225-1232.

50. Gibson, D.T., S.M. Resnick, K. Lee, J.M. Brand, D.S. Torok, L.P. Wackett and B.E. Haigler (1995) Desaturation, dioxygenation, and monooxygenation reactions catalyzed by naphthalene dioxygenase from Pseudomonas sp. strain 9816-4. J. Bacteriol. 177:2615-2621.

51. Wackett, L.P. (1995) Recruitment of cometabolic enzymes for environmental detoxification of organohalides. Env. Health Persp. 103:45-48.

52. Ellis, L.B.M. and L.P. Wackett (1995) A microbial biocatalysis database. Soc. Ind. Microbiology News 45:167-172. Feature paper and cover photograph.

53. Selifonov, S.A., J.E. Gurst and L.P. Wackett (1995) Regiospecific dioxygenation of ortho-trifluoromethylbenzoate by Pseudomonas aeruginosa 142: Evidence for 1,2-dioxygenation as a mechanismin ortho-halogenzoate dehalogenation. Biochem. Biophys. Res. Comm. 213:759-767.

54. DeSouza, M.L., L.P. Wackett, K.L. Boundy-Mills, R.T. Mandelbaum and M.J. Sadowsky (1995) Cloning, characterization, and expression of a gene region from Pseudomonas sp. strain ADP involved in the dechlorination of atrazine. Appl. Environ. Microbiol. 61:3373-3378.

55. Newman, L.M. and L.P. Wackett (1995) Purification and characterization of toluene 2-monooxygenase from Burholderia cepacia G4. Biochemistry 34:14066-14076.

56. Wackett, L.P. (1995) Bacterial cometabolism of organic compounds. In L. Young and C. Cerniglia (eds.) Microbial Transformation and Degradation of Toxic Organic Chemicals, Wiley-Liss, Inc., New York, p. 217-241.

57. Wackett, L.P. (1995) Biodehalogenation: Natural and engineered systems. In R. Hinchee, ed. Proceedings of the Third International In Situ and On-site Boreclamation Symposium, p. 105 -114.

58. Whiting, A.K., Y.R. Boldt, M.P. Hendrich, L.P. Wackett and L. Que, Jr. (1996) A Mn(II)-dependent extradiol cleaving catechol dioxygenase from Arthrobacter globiformis CM-2. Biochemistry 35:160-170.

59. Wackett, L.P. (1996) Biodegradation of chlorinated aliphatic compounds. In R. Crawford, ed. Bioremediation: Principles and Applications, pp. 300-311, Cambridge University Press, Cambridge, UK.

60. Wackett, L. P. & Ellis, L. B. M. (1996) The University of Minnesota Biocatalysis/Biodegradation Database: A Novel Microbiological Method. J. Microbiol. Methods 25:91-93.

61. DeSouza, M.L., M.J. Sadowsky and L.P. Wackett (1996) Atrazine chlorohydrolase from Pseudomonas sp. strain ADP: Gene sequence, enzyme purification and protein characterization. J. Bacteriol. 178: 4894-4900.

62. Wackett, L.P. (1996) Cometabolism: Is the emperor wearing clothes? Curr. Op. Biotech. 7:321-325.

63. Wackett, L.P. (1997) Biodegradation of halogenated solvents. In: R. Crawford, ed. Manual of Environmental Microbiology, American Society for Microbiology Press, pp.784-789.

64. Newman, L.N. and L.P. Wackett (1997) Trichloroethylene oxidation by purified toluene 2-monooxygenase: Products, kinetics and turnover-dependent inactivation. J. Bacteriol. 179:90-96.

65. Boldt, Y.R., A.K. Whiting, M.L. Wagner, M.J. Sadowsky, L.Que, Jr, and L.P.Wackett (1997) Manganese(II) active site mutants of 3,4-dihydroxyphenylacetate 2,3-dioxygenase from Arthrobacter globiformis strain CM-2. Biochemistry 36:2147-2153.

66. Wackett, L. P., C. L. Lange & R. L. Ornstein (1997) Optimizing biodegradation: Search, select, sssemble and systematize. In R. L. Ornstein, ed., Hanford Symposium on Health and the Environment, p. 289-298.

67. Boundy-Mills, K.L., M.L. DeSouza, R.T. Mandelbaum, L.P. Wackett and M.J. Sadowsky (1997) The atzB gene of Pseudomonas sp. strain ADP encodes the second enzyme of a novel atrazine degradation pathway. Appl. Environ. Microbiol. 63:916-923.

68. Hur, H-G., Newman, L.N., L.P. Wackett and M.J. Sadowsky (1997) Toluene 2-monooxygenase-dependent growth of Burkholderia cepacia strain G4/PR1 on diethyl ether. Appl. Environ. Microbiol. 63:1606-1609.

69. Lange, C. C. and L.P. Wackett (1997) Oxidation of aliphatic olefins by toluene dioxygenase: Enzyme rates and product identification. J. Bacteriol. 179:3858-3865.

70. Wackett, L.P. (1997) Designing metabolic pathways for the biodegradation of halogenated compounds. In S.K. Sikdar, ed. Bioremediation: Principles and Practice ,p. 435-456, Technomics Publishers, Basel.

71. Wackett, L.P. (1997) Biocatalysis, biodegradation, and bioinformatics. J. Ind. Microbiol. Biotechnol. 18:350-354.

72. Ellis, L.B.M. and L.P. Wackett (1997) Microbial biocatalysis and biodegradation informatics. Nature Biotechnology 15:1406.

73. M.J. Sadowsky, L.P. Wackett, M.L. de Souza, K.L. Boundy-Mills, and R. T. Mandelbaum (1998) Genetics of atrazine degradation in Pseudomonas spp. strain ADP, In L. Ballantine, J. McFarland, D. Hackett, eds., Triazine Herbicides: Risk Assessment, American Chemical Society Symposium Series vol. 683, p. 88-94.

74. Wackett, L. P., M. J. Sadowsky, M. L. de Souza, and R. T. Mandelbaum (1998) Enzymatic hydrolysis of atrazine, In L. Ballantine, J. McFarland, D. Hackett, eds., Triazine Herbicides: Risk Assessment, American Chemical Society Symposium Series vol. 683, p. 82-87.

75. DeSouza, M. L., M. J. Sadowsky, J. Seffernick, B. Martinez, and L. P. Wackett (1998) The atzABC genes encoding atrazine catabolism are widespread and highly conserved. J. Bacteriol. 180:1951-1954.

76. DeSouza, M.L., D. Newcombe, S. Alvey, D.E. Crowley, A. Hay, M.J. Sadowsky, and L.P. Wackett (1998) Molecular basis of a bacterial consortium: Interspecies catabolism of atrazine. Appl. Environ. Microbiol. 64:178-184.

77. Sadowsky, M.J., M.L. DeSouza, Z. Tong, and L.P. Wackett (1998) AtzC is a member of the amidohydrolase protein superfamily and is homologous to other atrazine-metabolizing enzymes. J. Bacteriol. 180:152-158.

78. DeSouza, M.L. , L.P. Wackett, and M.J. Sadowsky (1998) The genes encoding atrazine catabolism are located on a self-transmissable plasmid in Pseudomonas sp. ADP. Appl. Environ. Microbiol. 64: 2323-2326.

79. Wackett, L.P. (1998) Directed evolution of new enzymes and pathways for environmental biocatalysis. Anal. NY Acad. Sci 864:142-152.

80. Wackett, L. P. (1998) Microbial enzymes in biodegradation. In R. Fass, Y. Flashner and S. Reuveny, Eds. Novel Apporaches for Bioremediation of Organic Pollutants, Kluwer Academic Publishers, New York, p. 95-103.

81. Lange, C.C., L.P. Wackett, K. Minton, and M. Daly (1998) Engineering a recombinant Deinococcus radiodurans for organopollutant degradation in radioactive mixed waste environments. Nature Biotechnology 16:929-933.

82. Cai, Baoli, S. Vuilleumier, and L.P. Wackett (1998) Site-directed mutagenesis of the dichloromethane dehalogenase gene from Methylosinus strain DM11. Weishengwu Xuebao 38:163-167.

83. Cai, B., S. Vuilleumier and L. Wackett (1998) Purification and characterization of the mutant enzyme W117F of the dichloromethane dehalogenase of Methylophilus sp. strain DM11. Anal. NY Acad. Sci. 864:210-213.

84. Ellis, L.B.M., C.D. Hershberger and L.P. Wackett (1999) The University of Minnesota Biocatalysis/Biodegradation Database: Specialized metabolism for functional genomics. Nucl. Acids Res. 27:373-376.

85. Wackett, L.P., L.B.M. Ellis, S.M. Speedie, C.D. Hershberger, H-J. Knackmuss, A.M. Spormann, C.T. Walsh, L.J. Forney, W.F. Punch, T. Kazic, M. Kanehisa, and D.J. Berndt (1999) Predicting microbial biodegradation pathways. ASM News 65:87-93.

86. Wackett, L.P. and L.B.M. Ellis (1999) Biocatalysis databases. Encyclopedia of Biotechnology, p. 260-267, Academic Press, New York.

87. Wackett, L.P. and L.B.M. Ellis (1999) Predicting biodegradation. Environ. Microbiol. 1: 119-124.

88. Wackett, L.P. (2000) Environmental biotechnology. Trends Biotechnol. 18:19-21.

89. Ellis, L.B.M., C.D. Hershberger and L.P. Wackett (2000) The University of Minnesota Biocatalysis/Biodegradation Database: Microorganisms, Genomics and Prediction. Nucl. Acids Res. 28:377-379.

90. Brim, H., S.C. McFarlan, J.K. Fredrickson, K.W. Minton, M. Zhai, L.P. Wackett and M.J. Daly (2000) Engineering Deinococcus radiodurans for metal remediation in radioactive mixed waste environments. Nature Biotech. 18:85-90.

91. Strong, L.C., H. McTavish, M. J. Sadowsky, L. P. Wackett (2000) Field-scale remediation of atrazine-contaminated soil using recombinantEscherichia coli expressing atrazine chlorohydrolase. Environ. Microbiol. 2:91-98.

92. Venkataswaran, A., S.C. McFarlan, D. Ghosal, A. Vasilenko, K. Makarova, L.P. Wackett and M.J. Daly (2000) Physiologic determinants of radiation resistance in Deinococcus radiodurans. Appl. Environ. Microbiol. 66:2620-2626.

93. Wackett, L.P. and N.C. Bruce (2000) Environmental biotechnology. Towards sustainability. Curr. Op. Biotech. 11:229-231.

94. Seffernick, J.L., G. Johnson, M.J. Sadowsky, and L.P. Wackett (2000) Substrate specificity of atrazine chlorohydrolase and atrazine-catabolizing bacteria. Appl. Environ. Microbiol. 66:4247-4252.

95. Liu, J., M. Viguroux, C.D. Hershberger, L.B.M. Ellis, L.P. Wackett, J.D. Varner (2000) Heuristic-based prediction of specialized metabolism. Intelligent Systems in Molecular Biology 2000. University of California Press.

96. Sadowsky, M.J. and L. P. Wackett (2001) Genetics of atrazine degradation by Pseudomonas sp. strain ADP and other bacteria. In: R.E. Haugland, R.M. Zablotowicz, and J. C. Hall (eds.), Pesticide Biotransformations in Plants and Microorganisms, p. 268-282, American Chemical Society, Washington, DC.

96. Ellis, L.B.M., C. D. Hershberger, E. M. Bryan, and L. P. Wackett (2001) The University of Minnesota Biocatalysis/Biodegradation Database: Emphasizing Enzymes. Nucl. Acids. Res. 29:340-343.

97. Wackett, L. P. (2001) The pathways of biodegradation. In (M. Dworkin, S. Falkow, E. Rosenberg, K-H. Schleifer, E. Steckebrandt, Eds.) The Prokaryotes (on-line version).

98. Liu, J., M.Vigouroux, C. D. Hershberger, L. B. M. Ellis, L. P. Wackett (2001) Heuristic-based prediction of specialized metabolic pathways. In Proceeding of the Ninth International Conference on Intelligent Systems in Molecular Biology, Copenhagen, Denmark.

99. Seffernick, J.L., M.L. deSouza, M.J. Sadowsky and L.P. Wackett (2001) Melamine deaminase and atrazine chlorohydrolase: 98% identical but functionally different. J. Bacteriol. 183:2405-2410.

100. Raillard, S-A., A. Krebber, Y. Chen, J.E. Ness, E. Bermudez, R. Trinidad, R. Fullem, C. Davis, M. Welch, J. Seffernick, L.P. Wackett, W.P.C. Stemmer and J. Minshull (2001) Novel enzyme activities and functional plasticity revealed by recombining homologous enzymes. Chem. Biol. 8: 891-898.

101. Martinez, B., J. Tomkins, L.P. Wackett, R. Wing, and M.J. Sadowsky (2001) Complete nucleotide sequence and organization of the atrazine catabolic plasmid pADP-1 from Pseudomonas sp. ADP. J. Bacteriol. 183:5684-5697.

102. Seffernick, J.L. and L.P. Wackett (2001) Rapid evolution of bacterial catabolic enzymes: A case study with atrazine chlorohydrolase. Biochemistry 40:12747-12753.

103. Wackett, L.P., M.J. Sadowsky, B. Martinez, N. Shapir (2002) Biodegradation of atrazine and related triazine compounds: From enzymes to field studies. Appl. Microbiol. Biotechnol. 58:39-45.

104. Wackett, L.P. (2002) Mechanism and applications of Rieske dioxygenases. Enz. Microbiol. Technol. 31:577-587.

105. Sajjaphan, K., , N. Shapir, A.K.Judd, L.P. Wackett and M.J. Sadowsky (2002) A novel psbA1 gene from a naturally-occurring atrazine-resistant cyanobacterial isolate. Appl. Environ. Microbiol. 68:1358-1366.

106. Wackett, L.P. (2002) Expanding the map of microbial metabolism. Environ. Microbiol. 4: 12-13.

107. Handelsman, J. and L.P. Wackett (2002) Microbial diversity: Sustaining the earth and industry. Curr. Op. Microbiol. 5:237-239.

108. Seffernick, J.L., N. Shapir, M. Schoeb, G. Johnson, M.J. Sadowsky, and L.P. Wackett (2002) Enzymatic degradation of chlorodiamino-s-triazine. Appl. Environ. Microbiol. 68: 4672-4675.

109. Shapir, N., J.P. Osborne, G. Johnson, M.J. Sadowsky and L.P. Wackett (2002) Purification, substrate range and metal center of AtzC: The N-isopropylammelide hydrolase involved in bacterial atrazine metabolism. J. Bacteriol. 184:5376-5384.

110. Seffernick, J.L., H. McTavish, J.P. Osborne, M.L. de Souza, M.J. Sadowsky and L. P. Wackett (2002) Atrazine chlorohydrolase from Pseudomonas sp. strain ADP is a metalloenzyme. Biochemistry 41:14430-14437.

111. Parales, R.E., N.C. Bruce, A. Schmid and L.P. Wackett (2002) Biodegradation, biotransformation and biocatalysis. Appl. Environ. Microbiol. 68:4699-4709.

112. Strong, L.C., C. Pedersen, M.J. Sadowsky, L.P. Wackett (2002) Arthrobacter aurescens TC1 metabolizes diverse s-triazine ring compounds. Appl. Environ. Microbiol. 68: 5973-5980.

113. Ellis, L.B.M., B.K. Hou, W. Kang and L.P. Wackett (2003) The University of Minnesota Biocatalysis/Biodegradation Database: Post genomic data mining. Nucl. Acids Res. 31:262-265.

114. Wackett, L.P. (2003) Pseudomonas putida – a versatile biocatalyst. Nature Biotech. 21:136-138.

115. Wackett, L.P. (2003) Evolution of new enzymes and pathways: Soil microbes adapt to s-triazine herbicides. In:J. J. Gan, P.C. Zhu, S. D. Aust, and A.T. Lemley (eds.), Pesticide Decontamination and Detoxification, American Chemical Society Symposium Series No. 863, Washington, DC, pp. 37-48.

116. Fruchey, I., N. Shapir, M.J. Sadowsky and L.P. Wackett (2003) On the origins of cyanuric acid hydrolase: Purification, substrates and prevalence of AtzD from Pseudomonas sp. ADP. Appl. Environ. Microbiol. 69:3653-3657.

117. Negrete-Raymond, A.C., B. Weder, and L.P. Wackett (2003) Catabolism of arylboronic acids by Arthrobacter nicotinovorans strain PBA. Appl. Environ. Microbiol. 69:4263-4267.

118. Hou, B.K., L.P. Wackett, and L.B.M. Ellis (2003) Microbial pathway prediction: A functional group approach. J. Chem. Inf. Comp. Sci. 43:1051-1057.

119. Wackett, L.P. A.G. Dodge, and L.B.M. Ellis. (2004) Microbial genomics and the periodic table. Appl. Environ. Microbiol. 70:647-655.

120. Vetting, M.W., L. P. Wackett, L. Que Jr., J. D. Lipscomb and D. H. Ohlendorf (2004) A crystallographic comparison of a manganese and an iron-dependent extradiol dioxygenase. J. Bacteriol. 186:1945-1958.

121. Wackett, L.P. (2004) Applications of genomics to biocatalysis and biodegradation. In (C.M. Fraser, T. Read and K.E. Nelson, eds.) Microbial Genomes. The Human Press, Inc., Totowa, New Jersey, pp. 443-459.

122. Wackett, L.P. (2004) Stable isotope probing in biodegradation research. Trends Biotechnol. 22:153-154.

123. Sajjaphan, K., N. Shapir, L.P. Wackett, M. Palmer, J. Tomkins, B. Blackmon, and M.J. Sadowsky (2004) The Arthrobacter aurescens TC1 atrazine catabolic genes trzN, atzB and atzC are linked on a 160 kb region and functional in E. coli. Appl. Environ. Microbiol. 70:4402-4407.

124. Wackett, L.P. (2004) Novel biocatalysis by database mining. Curr. Op. Biotech. 15: 280-284.

125. Hou, B.K., L.B.M. Ellis, and L.P. Wackett (2004) Encoding microbial metabolic logic: Predicting biodegradation. J. Ind. Microbiol. Biotechnol. 31:261-272.

126. Wackett, L.P. (2004) Evolution of enzymes for the metabolism of new chemical inputs in the environment. J. Biol.Chem. 279:41259-41262 (mini-review).

127. Daly, M.J., E. K. Gaidamakova, V. Y. Matrosova, A. Vasilenko, M. Zhai, A. Venkateswaran, M. Hess, M. V. Omelchenko, H. M. Kostandarithes, K. S. Makarova, L. P. Wackett, J. K. Fredrickson, and D. Ghosal (2004) Accumulation of Mn(II) in Deinococcus radiodurans facilitates gamma-radiation resistance. Science 306:1025-1028.

128. Dodge, A.G. and L.P. Wackett (2005) Metabolism of bismuth subsalicylate and intracellular accumulation of bismuth by Fusarium sp. BI. Appl. Environ. Microbiol. 71:876-882.

129. Shapir, N, C. Rosendahl, G. Johnson, M. Andreina, M.J. Sadowsky and L.P. Wackett (2005) Substrate specificity and colorimetric assay for recombinant TrzN derived from Artheobacter aurescens TC1. Appl. Environ. Microbiol. 71:2214-2220.

130. Ghosal, D., M.V. Omelchenko, V.Y. Matrosova, A. Vasilenko, E.K. Gaidamakova, M. Zhai, H.K. Kostandaithes, K.S. Makarova, L.P. Wackett, J.K. Fredrickson, and M.J. Daly (2005) Rethinking how radiation kills cells: Survival of Deinococcus radiodurans and Shewanella oneidensis viewed from the perspective of systems that produce and defend against oxidative stress. FEMS Microbiol. Rev. 29:361-375.

131. Shapir, N.C., M.J. Sadowsky, and L.P. Wackett (2005) Purification and characterization of allophanate hydrolase (AtzF) from Pseudomonas sp. ADP. J. Bacteriol. 187:3731-3738.

132. Cheng, G., N. Shapir, M.J. Sadowsky, and L.P. Wackett (2005) Allophanate hydrolase, not urease, functions in bacterial cyanuric acid metabolism. Appl. Environ. Microbiol. 71:4437-4445.

133. Strong, L.C. and L.P. Wackett (2005) Engineering of bioremdiation processes: A critical review. In (M. Fingerman, Ed) Bioremdiation for Aquatic and Terrestrial Ecosystems.

134. Wackett, L.P. and L.B.M. Ellis (2005) Biodegradation of organic pollutants. Nature Encyclopedia.

135. Wang, L., D.A. Samac, N. Shapir, L.P. Wackett, C.P. Vance, and M.J. Sadowsky (2005) Biodegradation of atrazine in transgenic plants expressing a modified bacterial atrazine chlorohydrolase (atzA) gene. Plant Biotechnol. J. 3:475-486.

136. Emerson, J.P., Wagner, M.L., M.F. Reynolds, L.Que, Jr., M.J. Sadowsky, and L.P. Wackett (2005) The role of histidine-200 in MndD, the Mn(II)-dependent 3,4-dihydroxyphenylacetate 2,3-dioxygenase from Arthrobacter globiformis strain CM-2, a site-directed mutagenesis study. J. Bioinorg. Chem. 10:751-760.

137. Ellis, L.B.M., D. Roe, and L.P. Wackett (2006) The University of Minnesota Biocatalysis/Biodegradation Database: The first decade. Nucl. Acids Res. 34: D517-D521.

138. Shapir, N.C., M.J. Sadowsky, and L.P. Wackett (2005) Purification and characterization of allophanate hydrolase (AtzF) from Pseudomonas sp. ADP. J. Bacteriol. 187:3731-3738.

139. Brim, H., J. P. Osborne, V.Y. Matrosova, M. Zhai, A. Venkateswaran, H.M. Kostandarithes, J. K. Fredrickson, L.P. Wackett, and M. J. Daly. (2006) Deinococcus radiodurans engineered for complete toluene degradation facilitates Cr(VI) reduction. Microbiology 152: 2469-2477.

140. Shapir, N. C. Pedersen, O. Gil, L. Strong, J. Seffernick, M.J. Sadowsky and L.P. Wackett (2006) TrzN from Arthrobacter aurescens TC1 is a zinc amidohydrolase. J. Bacteriol. 188: 5859-5864.

141. Dodge, A.G., J.R. Richman, G. Johnson, and L.P. Wackett (2006) Thioamide metabolism by Ralstonia picketii TA. Appl. Environ. Microbiol. 72:7468-7476.

142. Mongodin, E.F., N. Shapir, S. C. Daugherty, R. T. DeBoy, J. Emerson, A. Shvartzbeyn, D. Radune, J. Vamathevan, V. Grinberg, H. Khouri, L. P. Wackett, K. E. Nelson, and M. J. Sadowsky (2006) Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1. PLOS Genetics 2: 20214-20220.

143. N. Shapir, E. F. Mongodin, M. J. Sadowsky, S. C. Daugherty, K. E. Nelson, and L. P. Wackett (2007) Evolution of catabolic pathways: genomic insights into microbial s-triazine metabolism. J. Bacteriol. 189:674-682.

144. Wackett, L.P. (2007) Pathways to discovering new microbial metabolism for functional genomics and biotechnology. Adv. Micro. Physiol.

61:219-232.

145. Seffernick, J.L., A. Aleem, J.P. Osborne, G. Johnson, M.J. Sadowsky and L.P. Wackett (2007)Hydroxyatrazine N-ethylaminohydrolase (AtzB): Characterization and insights into active site architecture of an amidohydrolase superfamily enzyme. J. Bacteriol. 189: 6989-6997.

146. Wackett, L.P., J. Frias, J.L. Seffernick, D. Sukovich, and S.M. Cameron (2007) Vibrio furnissii M1: Genomic and biochemical studies demonstrating the absence of an alkane-producing phenotype. Appl. Environ. Microbiol. 73: 7192-7198.

147. Wackett, L.P. (2008) Biomass to fuels via microbial transformations. Curr. Op. Chem. Bio. 12:1-7.

148. Mandelbaum, R.T., M.J. Sadowsky, and L.P. Wackett (2008) Microbial degradation of s-triazine herbicides. In: H. LeBaron, J. McFarland, and O. Burnside (eds.), The Triazine Herbicides, Elsevier, Amsterdam.

149. Wackett, L.P. (2008) Microbial-based motor fuels: Science and technology. Microbial Biotechnol. 1: 211-225.

150. Gross, C., R. Felsheim, and L.P. Wackett (2008) Genes and enzymes of azetidine-2-carboxylate metabolism: Detoxification and assimilation of an antibiotic. J. Bacteriol. 190: 4859-4864.

152. Ellis, L.B.M., J. Gao, K. Fenner, and L.P. Wackett (2008) The University of Minnesota pathway prediction system: predicting metabolic logic. Nucl. Acids Res. 36:W427-W432.

153. Fenner, K., J. Gao, S. Kramer, L. Ellis, and L.P. Wackett (2008) Data-driven extraction of relative reasoning rules to limit combinatorial explosion in biodegradation pathway prediction. Bioinformatics 24: 2079-2085.

154. Frias, J.A., J.E. Richman, and L.P. Wackett (2009) C29 olefinic hydrocarbons biosynthesized by Arthrobacter species. Appl. Environ. Microbiol. 75:1774-1777.

155. Wackett, L.P. and L.B.M. Ellis (2009) Mechanisms of degradation of synthetic chemicals. Handbook of Environmental Chemistry, Springer-Verlag, Berlin, p.3-16.

156. Wackett, L.P. and L.B.M. Ellis (2009) Microbial biodegradation database and prediction. Encyclopedia of Microbiology, 3rd Ed. (M. Schaechter, ed.), Elsevier Press, p. 78-87.

157. Wackett, L.P. (2009) Questioning our perceptions about the evolution of biodegradative enzymes. Curr. Op Microbiol. 12:244-251.

158. Seffernick, J.L., S.K. Samanta, T.M. Louie, L.P. Wackett and M. Subramanian (2009) Investigative mining of sequence database for novel enzymes: A case study with nitrilases. J. Biotechnol. 143:17-26.

159. Li, Q., J.F. Seffernick, M.J. Sadowsky and L.P. Wackett (2009) Thermostable cyanuric acid hydrolase from Moorella thermoacetica ATCC 39073. Appl. Environ. Microbiol. 75:6986-6991.

160. Wackett, L.P. and L.B.M. Ellis (2009) Database tools for biocatalysis. Encyc. Ind. Biotech. (in press).

161. Wicker, J., K. Fenner, L. Ellis, L.P. Wackett and S. Kramer (2009) Machine learning and data mining approaches to biodegradation pathway prediction. Proceedings of the 2nd International Workshop on Induction of Process Models.

162. Wackett, L.P. (2009) Aliphatic hydrocarbons - Producing microorganisms. Handbook of Hydrocarbon Microbiology, Springer, Heidelberg.

163. Wackett, L.P. (2009) Aliphatic hydrocarbons, C-C bond formation. Handbook of Hydrocarbon Microbiology, Springer, Heidelberg.

164. Wackett, L.P. (2009) Biofuels. Handbook of Hydrocarbon Microbiology, Springer, Heidelberg.

165. Wackett, L.P. and L.B.M. Ellis (2009) University of Minnesota Biocatalysis/Biodegradation Database and hydrocarbon research. Handbook of Hydrocarbon Microbiology, Springer, Heidelberg.

166. Wackett, L.P. (2009) Web resources: Hydrocarbons. Handbook of Hydrocarbon Microbiology, Springer, Heidelberg.

167. Gao, J., L.B.M. Ellis, and L.P. Wackett (2010) The University of Minnesota Biocatalysis/Biodegradation Database: Improving public access. Nucl. Acids Res. D488-D491.

169. Seffernick, J.L., A.G. Dodge, M.J. Sadowsky, J.A. Bumpus, and L.P. Wackett (2010) Bacterial ammeline metabolism by guanine deaminase. J. Bacteriol. 192:1106-1112.

170. Wicker, J., K. Fenner, L.B.M. Ellis, L.P. Wackett and S. Kramer (2010) Predicting biodegradation products and pathways: A hybrid knowledge-based and machine learning based approach. Bioinformatics 26: 814-821. doi:10.1093/ bioinformatics/btq024.

171. Sukovich, D.J., J.L. Seffernick, J.E. Richman, K.A. Hunt, J.A. Gralnick, and L.P. Wackett (2010) Structure, function and insights into the biosynthesis of a head-to-head hydrocarbon in Shewanella oneidensis strain MR-1. Appl. Environ. Microbiol.76:3842-3849 .

172. Sukovich, D.J., J.L. Seffernick, J.E. Richman, J.A. Gralnick, and L.P. Wackett (2010) Widespread head-to-head hydrocarbon biosynthesis in bacteria and role of OleA. Appl. Environ. Microbiol. 76:3850-3862.

173. Toyoda, M, K. Jitsumori, B. Mikami, L.P. Wackett, T. Kurihara, and N. Esaki (2010) Crystallization and preliminary X-ray analysis of L-azetidine-2-carboxylate hydrolase from Pseudomonas sp. strain 2AC. Acta Crystallographica Section F 66:801-804.

174. Seffernick, J.L., E. Reynolds, A.A. Federov, E. Federov, S.C. Almo, M.J. Sadowsky, and L.P. Wackett (2010) X-ray structure and mutational analysis of the atrazine chlorohydrolase TrzN. J. Biol. Chem. 285:30606-30614.

175. Frias, J.A., B.R. Goblirsch, L.P. Wackett, and C.M. Wilmot (2010) Cloning, purification, and crystallization of the OleC protein from Stenotrophomonas maltophilia involved in head-to-head hydrocarbon biosynthesis. Acta Crystallographica Section F 66:1108-1110.

176.  Wackett, L.P. (2011) Engineering microbes to produce biofuels. Curr. Op. Biotech. 22:388-393.

177.  Gao, J., L.B.M. Ellis, and L.P. Wackett (2011) The University of Minnesota Pathway Prediction System: Multi-level prediction and visualization. Nucl. Acids Res. W406-411.

178.  Frias, J.A., J.E. Richman, J.S. Erickson and L.P. Wackett (2011) Purification and characterization of OleA from Xanthomonas campestris and demonstration of a non-decarboxylative Claisen condensation reaction. J. Biol. Chem. 286:10930-10938.

179.  Pinzon, N., K. Aukema, J.A. Gralnick, and L.P. Wackett (2011) Nile Red screening for the bacterial production of hydrocarbons and ketones. mBio  2(4): pii: e00109-11. doi:10.1128/mBio.00109-111.

180.  Frias, J.A., J.E. Richman, J.S. Erickson and L.P. Wackett (2011) Letter: Definitive alkene identification needed for in vitro studies with Ole (olefin biosynthesis) proteins. J. Biol. Chem. 286 (26): le 12-13.

181.  Cameron, S.M., K. Durchschein, J.E. Richman, M.J. Sadowsky and L.P. Wackett (2011) A new family of biuret hydrolases involved in s-triazine ring metabolism. ACS Catalysis 1(9):1075-1082.

182.  Reátegui,E, E. Reynolds,L. Kasinkas, A. Aggarwal, M.J. Sadowsky,A. Aksan, L.P. Wackett (2012) Silica gel encapsulated AtzA biocatalyst for atrazine biodegradation. Appl. Micro. Biotech. Jan 7. E-pub ahead of print.

183.  Wackett, L.P. and L.B.M. Ellis (2012) MiniReview: Microbial transformation of organic compounds. Micro. Inf. Exp. 2:1 doi:10.1186/2042-5783-2-1

184.  Dodge, A.G., L.P. Wackett, and M.J. Sadowsky (2012) Melamine metabolism by Rhodococcus sp. Mel. Appl. Environ. Microbiol. 78:1397-1403.

185.  Goblirsch, B.R., J.A. Frias, L.P. Wackett, and C.M. Wilmot (2012) Crystal structures of Xanthomonas campestris OleA reveal features that promote head-to-head condensation of two long chain fatty acids. Biochemistry 51: 4138-4146.

186.  Seffernick, J.L., J.S. Erickson, S. Cho, A.G. Dodge, J. Richman, S.M. Cameron, M.J. Sadowsky, and L.P. Wackett (2012) Defining the cyanuric acid hydrolase (AtzD)/barbiturase protein family. J. Bacteriol. 194: 4579-4588.

187.  Wackett, L.P. and C.M. Wilmot (2013) Hydrocarbon biosynthesis in microorganisms. In (M.E. Himmel, Ed.) Direct Microbial Conversion of Biomass to Advanced Biofuels. Elsevier, New York (in press).

188.  Strong, L.C., T. Gould, L. Kasinkas, A. Aksan, and L.P. Wackett (2013) Biodegradation in produced waters: Chemistry, microbiology and engineering. J. Environ. Eng. 140 (5): B4013001-1 to B4013001-8. doi: 10.1061/(ASCE)EE.1943-7870.0000792.

189.  Fenner, K. S. Canonica, L.P. Wackett and M. Elsner (2013) Evaluating pesticide biodegradation in the environment: Blind spots and emerging opportunities.Science 341: 752-758.

190.  Cho, S., K. Shi, L.P. Wackett and H. Aihara (2013) Crystalization and preliminary X-ray diffraction studies of cyanuric acid hydrolase from Azorhizobium caulinodans. Acta crystallographica Section F 69:880-883.

191.  Mutlu, B.R., S. Yeom, H.-W. Tong, L.P. Wackett and A. Aksan (2013) Silicon-alkoxide cross-linked nanoparticle gels for encapsulation of bacterial biocatalysts. J. Mater. Chem. A 1: 11051-11060.

192.  Aukema, K, T. Makris, S. Stoian, J. Richman, E Munck, J.D. Lipscomb, and L.P. Wackett (2013) Cyanobacterial aldehyde deformylase oxygenation of aldehydes yields n-1 aldehydes and alcohols in addition to alkanes. ACS Catalysis 3: 2228-2238.

193.  Tong, H.-W., B.R. Mutlu, L.P. Wackett and A. Aksan. (2013) Silica/PVA biocatalytic nanofibers. Materials Lett. 111:234-237.

194.  Dodge, A.G., C.S. Preiner, and L.P. Wackett (2013) Expanding the cyanuric acid hydrolase protein family to the fungal kingdom. J. Bacteriol. 195: 5233-5241.

195.  Tong, H.-W., B.R. Mutlu, L.P. Wackett, and A. Aksan (2014) Manufacturing of bioreactive nanofibers for bioremediation. Biotech. Bioeng. 111(8): 1483-1493.doi: 10.1002/bit.25208.

196.  Aukema, K.A., L. Kasinkas, A. Aksan, L.P. Wackett (2014) Biodegradation of novel hydrocarbon ring structures found in hydraulic fracturing waters using silica-encapsulated Pseudomonas sp. NCIB9816-4. Appl. Environ. Microbiol. 80: 4968-4976.

197.  Cho, S.,  K. Shi, J.L. Seffernick, A.G. Dodge, L.P. Wackett, and H. Aihara (2014) Cyanuric acid hydrolase from Azorhizobium caulinodans ORS 571: Crystal structure and insights into a new class of ser-lys dyad proteins. PLOS ONE 2014 Jun 10;9(6):e99349. doi: 10.1371/journal.pone.0099349.

198.  Vail, A.W., P. Wang, H. Uefuji, D.A. Samac, C.P. Vance, L.P. Wackett, and M.J. Sadowsky (2014) Biodegradation of atrazine by three transgenic grasses and alfalfa expressing a modified bacterial atrazine chlorohydrolase gene. Transgenic Res. Nov 29, epub ahead of print. PMID: 25432082.

199.  Mutlu, B.R., S. Yeom, L.P. Wackett, and A. Aksan (2015) Modelling and optimization of a bioremediation system utilizing silica gel encapsulated whole-cell biocatalyst. Chem. Eng. J. 259: 574-580.

200.  Dodge, A.G., K. Carrasquillo, L. Rivera, L. Xu, L.P. Wackett and M.J. Sadowsky (2015) A rapid detection method for L-abrine in food as a marker for the toxic protein abrin using two microbial enzymes. Appl. Environ. Microbiol. 81: 1610-1615.

201.  Mutlu, B.R., K. Hirschey, L.P. Wackett, and A. Aksan (2015) Optimization of aging, drying and storage conditions for biocatalytic silica gel. J.Sol-Gel Sci. Technol. 74: 823-833. DOI 1007/s10971-015-3690-8.

202.  Schürner, H., J.L. Seffernick, A. Grzybkowska, A. Dybala-Defratyka, L.P. Wackett, and M. Elsner (2015) Characteristic isotope fractionation patterns in s-triazine degradation have their origin in multiple protonation sites in the s-triazine hydrolase TrzN. Environ. Sci. Technol. 49: 3490-3498.

203. Yeom, S., B. Mutlu, A. Aksan, and L.P. Wackett (2015) Bacterial cyanuric acid hydrolases for water treatment. Appl. Environ. Microbiol. 81:6660-6668.

204. Radian, A., K.A. Aukema, A. Aksan, L.P. Wackett (2015) A silica gel for enhanced activity and hypochlorite-protection of cyanuric acid hydrolase in a recombinant E. colimBio 6(6). Pii: e01477-15.doi:10.1128/mBio.01477-15. PMID: 26530383.

205. Wackett, L.P. and C.M. Wilmot (2015) Hydrocarbon biosynthesis in microorganisms. In (M.E. Himmel, Ed.) Direct Microbial Conversion of Biomass to Advanced Biofuels.p. 13-33. Elsevier, New York.

206. Sakkos, J.K., D.P. Kieffer, B.R. Mutlu, L.P. Wackett and A. Aksan (2016) Design of a silica encapsulation platform using a model hydrocarbon degrader Pseudomonas sp. NCIB 9816. Biotechnol. Bioeng.113: 3513-521. doi: 10.1002/bit.25821. PMID: 26332745.

207. Seffernick, J.L. and L.P. Wackett (2016) Ancient and recent evolution converge for the biodegradation of cyanuric acid and related triazines. Appl. Environ. Microbiol. 82: 1638-1645. PMID: 26729715.