The department of Biochemistry, Molecular Biology and Biophysics is committed to understanding the molecular mechanisms of metabolic diseases and cancer; developing novel strategies in biocatalysis and biotechnology; and advancing knowledge through structural biology and molecular biophysics. Please enjoy a collection of news, features and opportunities for and about BMBB.
We’re a medicated society — and because many pharmaceuticals can pass through our bodies without being degraded, we have medicated wastewater as well. Scientists have found scores of different drugs in water flowing into wastewater treatment plants.
Unprecedented images of cancer genome-mutating enzymes acting on DNA provide vital clues into how the enzymes work to promote tumor evolution and drive poor disease outcomes. These images, revealed by University of Minnesota researchers, provide the first ever high-resolution pictures of molecular complexes formed between DNA and the human APOBEC3A and APOBEC3B enzymes.
The research is published today online in Nature Structural and Molecular Biology.
The first round of University of Minnesota Grand Challenges Research grants, totaling $3.6 million, were awarded to 29 teams of faculty from across the Twin Cities campus. The research collaborations address the University's five interrelated Grand Challenges areas of special focus, with one integrative initiative spanning multiple areas. Areas of focus include: