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GCD Research

Research news from Genetics, Cell Biology and Development. 

Fine-tuning the quest to understand protein function—and malfunction

Daniel Schmidt

Sometimes the best way to figure out how something works is to break it. In the case of a protein, that often takes the form of altering genes so the proteins they encode have extra amino acids in various locations. An insertion that makes it impossible for the protein to do its job right likely has hit an Achilles’ heel – a region that is integral to proper function.