- Cultured dental plaque samples were used as a surrogate for the oral environment.
- Metaproteomics identified metabolic pathways differentially regulated in response to diet.
- Selected reaction monitoring (SRM) used to quantify conserved peptides from three enzymes which increase in abundance in sucrose-induced dysbiosis.
- Shown: NADP-specific glutamate dehydrogenase (EC 1.4.1.4) strongly upregulated in response to sucrose.
