Sinha et al. are currently studying characteristics of prostate cancer stem cells and aggressiveness of prostate cancer in addition to cell proliferation and cell death.
Selected Publications (Pubmed Search)
Sinha, AA., Fernandes, E., Ewing, S., Wilson, M.: Prediction of immune surveillance responsive metastic prostate cancer in pelvic lymph node and emergence of surveillance unresponsive/resistant metastic cells. Anticancer Research 33: 3635-3644, 2013
Qian, J, Bostwick, DG., Iczkowski KA, Lang K, Betre K, Wilson MJ, Le C, Sinha AA: Characterization of prostate cancer in needle biopsy by cathepsin B, cell proliferation, and DNA ploidy. In Press, Anticancer Research, February 2010.
Phillips JL and Sinha AA: Patterns, Art, and Context:Donald Floyd Gleason and the Development of the Gleason Grading System. Urology 74: 497–504, 2009.
Wang X, Wilson, MJ, Slaton JW, Sinha AA, Ewing SL, Pei D: Increased aggressiveness of human prostate PC-3 tumor cells expresssing cell surface membrane type-1 matrix metalloproteinase (MT1-MMP). J. Androl. 30: 259-274, 2009.
Sinha, A. A., Morgan, J. L., Betre, K., Wilson, M. J., Le, C. and Marks, L. S.: Cathepsin B expression in Native Japanese and Japanese-American prostate cancer patients: An immunohistochemical study. Anticancer Res., 28:2271-2278, 2008.
Wilson, M. J. and Sinha, A. A.: Matrix degradation in prostate cancer. In: Cancer Metastasis-Biology and Treatment, Metastasis of Prostate Cancer. Volume 10, Ablin, R. J. and Mason, M.D. editors, Springer Science and Business Media B.V., Dordrecht, The Netherlands, 2008, pages 221-251.
Sinha AA, Morgan JL, Buus RJ, Ewing SL, Fernandes ET, Le C, Wilson MJ: Cathepsin B Expression is Similar in African-American and Caucasian Prostate Cancer Patients. Anticancer Res. 27:3135-3142, 2007.
Sinha AA, Quast BJ, Wilson MJ, Fernandes ET, Reddy PK, Ewing SL, Gleason DF: Prediction of pelvic lymph node metastasis by the ratio of cathepsin B to stefin (cystatin) A in human prostate cancer. Cancer 94: 3141-3149, 2002.