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Lex Flagel

Adjunct Faculty

Expertise:


Google Scholar Profile

Curriculum Vitae


Education

B.S., University of Minnesota, 2003
Ph.D., Iowa State University, 2009

Research Statement

I am an adjunct professor in the Plant and Microbial Biology Department at the University of Minnesota-Twin Cities. In addition, I am also a research scientist and group lead in the Plant Breeding division of Bayer Crop Science. At Bayer my team and I use genomics and statistics to improve crop yields. Due to my unique position with one foot in academia and one in industry, I also engage in helping undergraduates, graduate students and post-docs explore diverse career opportunities and am happy to chat with interested students.

Publications

Boaventura, D., J. Ulrich, B. Lueke, A. Bolzan, D. Okuma, O. Gutbrod, S. Geibel, Q. Zeng, P. Dourado, S. Martinelli, L. Flagel, G. Head, and R. Nauen. 2020. Molecular characterization of Cry1F resistance in fall armyworm, Spodoptera frugiperda from Brazil. Insect Biochemistry and Molecular Biology. 116: 1-11

Flagel, L.​, B. K. Blackman, L. Fishman, P. J. Monnahan, A. Sweigart, and J. K. Kelly. 2019.​ ​ GOOGA: A platform to synthesize mapping experiments and identify genomic structural diversity. PLoS Computational Biology ​ 15(4): e1006949

Flagel, L.​, Y. Brandvain, and D. Schrider. 2019. The unreasonable effectiveness of convolutional neural networks in population genetic inference.  Molecular Biology and Evolution. 36: 220-238

Khajuria, C., S. Ivashuta, E. Wiggins, ​ L. Flagel​, W. Moar, M. Pleau, K. Miller, Y. Zhang, P. Ramaseshadri, C. Jiang, T. Hodge, P. Jensen, M. Chen, A. Gowda, B. McNulty, C. Vazquez, R. Bolognesi, J. Haas, G. Head, and T. Clark. 2018. Development and characterization of the first dsRNA-resistant insect population from western corn rootworm, ​ Diabrotica virgifera virgifera ​ LeConte. PLoS One  13: e0197059.

Flagel, L.​, Y. W. Lee, H. Wanjugi, S. Swarup, A. Brown, J. Wang, E. Kraft, J. Greenplate, J. Simmons, N. Adams, Y. Wang, S. Martinelli, J.A. Haas, A. Gowda, and G. Head. 2018. Mutational disruption of the ​ ABCC2 ​ gene in fall armyworm, ​Spodoptera frugiperda, confers resistance to the Cry1Fa and Cry1A.105 insecticidal proteins. ​Scientific Reports 8: 7255

Flagel, L., Y. Brandvain, and D. Schrider. 2018. The unreasonable effectiveness of convolutional neural networks in population genetic inference. Bioaxiv. https://proxy.qualtrics.com/proxy/?url=https%3A%2F%2Fdoi.org%2F10.1101%2F336073&token=PW81pfncPLvCEFhrfX5ibGDBY%2B7AKTG5Oy%2BKMRmBu60%3D

Flagel, L., B.K. Blackman, L. Fishman, P.J. Monnahan, A. Sweigart, J.K. Kelly. 2018. A synthesis of mapping experiments reveals extensive genomic structural diversity in the Mimulus guttatus species complex. Bioaxiv. https://proxy.qualtrics.com/proxy/?url=https%3A%2F%2Fdoi.org%2F10.1101%2F330159&token=AnmGP0lSafCfZNrq9sVnUFwiJsyFArqleF8Ke3qkYRo%3D

McGaugh, S.E., A.M. Bronikowski, C.H. Kuo, D.M. Redding, E.A. Addis, L.E. Flagel, F.J. Janzen, and T.S. Schwartz. 2015. Rapid molecular evolution across amniotes of the IIS/TOR network. PNAS. 112: 7055-7060.

Sweigart, A. L. and L. E. Flagel. 2015. Evidence of natural selection acting on a polymorphic hybrid incompatibility locus in Mimulus. Genetics. 199: 543-554.

Flagel, L.E., S. Swarup, M. Chen, C. Bauer, H. Wanjugi, M. Carroll, P. Hill, M. Tuscan, R. Bansal, R. Flannagan, T. Clark, A.P. Michel, G.P. Head, and B.S. Goldman. 2015. Genetic markers for Western Corn Rootworm resistance to Bt toxin. G3. 5: 399-405.

Brandvain, Y., A Kenney, L. Flagel, G. Coop, and A. Sweigart. 2014. Speciation and introgression between Mimulus nasutus and Mimulus guttatus. PloS Genetics. 10: e1004410.

Flagel, L., J. Willis, T. Vision. 2014. The standing pool of genomic structural variation in a natural population of Mimulus guttatus. Genome Biology and Evolution. 6: 53-64.

P:
636-328-5376
E:

flag0010@umn.edu

358 Biological Sciences Center
1445 Gortner Avenue
St. Paul, MN 55108