PAST WORK EXPERIENCE
- Develop new cell based immunofluorescence diagnostic products and processes in conformance with ISO and FDA regulatory standards, conduct preliminary research and feasibility studies for potential diagnostic biomarkers
- Improve quality of existing cell culture based manufacturing products, quality systems and processes in adherence to GMP, ISO and FDA; Increased manufacturing quality control pass rate by 34%
- Contribute to IP development, completion of regulatory requirements and transfer of technology to manufacture new diagnostic products
- Techniques utilized: Cell culture, lipid and non-lipid based transfections, lentiviral transductions, western blot, direct and indirect immunofluorescence
I moved to Minneapolis in the fall of 2014 from Buffalo, NY to work on the exciting drug discovery platform that was developed in Thomas Lab in collaboration with Fluorescence Innovations.
My job duties evolved from performing cell-based assays to managing and consulting on the biosensor development process in through our core facility at the Biophysical Technology Center. A summary of my position with Thomas Lab is as follows:
- Drive in new research collaborations in line with competitive strategy for drug discovery projects
- Coordinate, manage, and supervise the Biosensor Development Division of a large laboratory (Thomas Laboratory, in BMBB Department), in collaboration with both academic and external collaborators for 5 federally and privately funded grants amounting to 1-5 M USD each.
- Manage cell culture facility at the Biophysical Technology Center.
- Train new employees; mentor, train and supervised students and interns
- Develop biosensors using patented technology for drug discovery projects
- Lead and direct process development and process improvement to implement Good Laboratory Practices (GLP) for high-throughput screening throughout the laboratory.
- Review literature and introduce new technology, contribute to intellectual property (IP) development and proposal preparation for projects related to high-throughput screening assays for discovering heart-failure drugs and other targets
- Contributed to 3 research publications on ongoing biosensor projects
- Techniques utilized: Cell Culture, PCR, cloning, mutagenesis, western blot, direct and indirect immunofluorescence, fluorescence lifetime and spectroscopic assays.