Office Address
1445 Gortner Avenue
St. Paul, MN 55108
United States
Lex
Flagel
Adjunct Faculty
Plant and Microbial Biology
Research statement
I am an adjunct professor in the Plant and Microbial Biology Department at the University of Minnesota-Twin Cities. In addition, I am also a research scientist and group lead in the Plant Breeding division of Bayer Crop Science. At Bayer my team and I use genomics and statistics to improve crop yields. Due to my unique position with one foot in academia and one in industry, I also engage in helping undergraduates, graduate students and post-docs explore diverse career opportunities and am happy to chat with interested students.
Selected publications
Boaventura, D., J. Ulrich, B. Lueke, A. Bolzan, D. Okuma, O. Gutbrod, S. Geibel, Q. Zeng, P. Dourado, S. Martinelli, L. Flagel, G. Head, and R. Nauen. 2020. Molecular characterization of Cry1F resistance in fall armyworm, Spodoptera frugiperda from Brazil. Insect Biochemistry and Molecular Biology. 116: 1-11
Flagel, L., B. K. Blackman, L. Fishman, P. J. Monnahan, A. Sweigart, and J. K. Kelly. 2019. GOOGA: A platform to synthesize mapping experiments and identify genomic structural diversity. PLoS Computational Biology 15(4): e1006949
Flagel, L., Y. Brandvain, and D. Schrider. 2019. The unreasonable effectiveness of convolutional neural networks in population genetic inference. Molecular Biology and Evolution. 36: 220-238
Khajuria, C., S. Ivashuta, E. Wiggins, L. Flagel, W. Moar, M. Pleau, K. Miller, Y. Zhang, P. Ramaseshadri, C. Jiang, T. Hodge, P. Jensen, M. Chen, A. Gowda, B. McNulty, C. Vazquez, R. Bolognesi, J. Haas, G. Head, and T. Clark. 2018. Development and characterization of the first dsRNA-resistant insect population from western corn rootworm, Diabrotica virgifera virgifera LeConte. PLoS One 13: e0197059.
Flagel, L., Y. W. Lee, H. Wanjugi, S. Swarup, A. Brown, J. Wang, E. Kraft, J. Greenplate, J. Simmons, N. Adams, Y. Wang, S. Martinelli, J.A. Haas, A. Gowda, and G. Head. 2018. Mutational disruption of the ABCC2 gene in fall armyworm, Spodoptera frugiperda, confers resistance to the Cry1Fa and Cry1A.105 insecticidal proteins. Scientific Reports 8: 7255
Flagel, L., Y. Brandvain, and D. Schrider. 2018. The unreasonable effectiveness of convolutional neural networks in population genetic inference. Bioaxiv. https://proxy.qualtrics.com/proxy/?url=https%3A%2F%2Fdoi.org%2F10.1101%2F336073&token=PW81pfncPLvCEFhrfX5ibGDBY%2B7AKTG5Oy%2BKMRmBu60%3D
Flagel, L., B.K. Blackman, L. Fishman, P.J. Monnahan, A. Sweigart, J.K. Kelly. 2018. A synthesis of mapping experiments reveals extensive genomic structural diversity in the Mimulus guttatus species complex. Bioaxiv. https://proxy.qualtrics.com/proxy/?url=https%3A%2F%2Fdoi.org%2F10.1101%2F330159&token=AnmGP0lSafCfZNrq9sVnUFwiJsyFArqleF8Ke3qkYRo%3D
McGaugh, S.E., A.M. Bronikowski, C.H. Kuo, D.M. Redding, E.A. Addis, L.E. Flagel, F.J. Janzen, and T.S. Schwartz. 2015. Rapid molecular evolution across amniotes of the IIS/TOR network. PNAS. 112: 7055-7060.
Sweigart, A. L. and L. E. Flagel. 2015. Evidence of natural selection acting on a polymorphic hybrid incompatibility locus in Mimulus. Genetics. 199: 543-554.
Flagel, L.E., S. Swarup, M. Chen, C. Bauer, H. Wanjugi, M. Carroll, P. Hill, M. Tuscan, R. Bansal, R. Flannagan, T. Clark, A.P. Michel, G.P. Head, and B.S. Goldman. 2015. Genetic markers for Western Corn Rootworm resistance to Bt toxin. G3. 5: 399-405.
Brandvain, Y., A Kenney, L. Flagel, G. Coop, and A. Sweigart. 2014. Speciation and introgression between Mimulus nasutus and Mimulus guttatus. PloS Genetics. 10: e1004410.
Flagel, L., J. Willis, T. Vision. 2014. The standing pool of genomic structural variation in a natural population of Mimulus guttatus. Genome Biology and Evolution. 6: 53-64.
Education and background