Publications by the Hackett Laboratory

  1. Cui, Z., K. Clark, C. Kaufman and P.B. Hackett (2001). Inhibitation of skiA and skiB gene expression ventralizes zebrafish embryos. Genesis 30: 149-153.

  2. Hackett, P.B. (2001). Genetic engineering: What are we fearing? Transgenic Res. 10: 1-3.

  3. Cui, Z., A.M. Geurts, G. Liu, C.D. kaufman and P.B. hackett (2002). Structure0Function analysis of the inverted terminal repeats of the Sleeping Beauty transposon. J. Mol. Biol. 318: 1221-1235.

  4. Dupuy, A.J., K. Clark, C. Carlson, S. Fritz, K. Finley, S. Ekker, P.B. Hackett, S. Horn, and D.A. Largaespada (2002) Mammalian germline transgenesis by transposition. Proc. Natl. Acad. Sci. UAS 99: 4495-4499.

  5. Cui.Z., Y. Yang, C.D. Kaurman, D. Agalliu and P.B. Hackett (2002). RecA-medicated, targeted mutagenesis in zebrafish. Mar. Biotech. 5: 174-184.

  6. Geurts, A.M., Y. Yang, K.J. clark, Z. Cui, A.J. Dupuy, D.A. Largaespada and P.B. Hackett (2003). High level gene transfer into genomes of human cells by the Sleeping Beauty transposon system. Mol. Therapy 8: 107-116.

  7. Belur, L., J. Frandsen, A. Dupuy, D.A. largaespaday, P.B. Hackett,a nd R.S. McIvor (2003). Gene insertion and long-term expression in lung medicated by the Sleeping Beauty transposon system. Mol. Therapy 8: 501-507

  8. Davidson, A.E., D. Balciunas, D. Mohn, J. Shaffer, S. Hermanson, S. Sivasubbu, P.B. Hackett, and S.C. Ekker (2003). Efficient gene delivery and expression in zebrafish using Sleeping Beauty. Dev. Biol. 263: 191-202.

  9. Kren, B.T., S.S. Gosh, C.L. Linehan, N. Roy Chowdhury, P.B. Hackett, J. Roy Chowdhury and C.J. Steer (2003). Hepatocyte-targeted delivery of Sleeping Beauty medicates efficient transposition in vivo. Gene Therap. Mol. Bio. 7: 229-238.

  10. Converse, A., L. Belur, J. Gori, G. Liu, F. Amaya, E. Aguilar-Cardova, P.B. Hackett,a nd R.S. McIvor (2004). Counterselection and co-delivery of transposon and tansposase functions for the study of Sleeping Beauty-medicated transposition in cultured mammalian cells. Somat. Cell. Mol. Genet. (in press).

  11. Lui, G,Z. Cui, E.L. Aronovich, C.B. Whitley and P.B. Hacktt (2004). Excision of Sleeping Beauty transposons: parameters an applications to gene therapy. J. Gene Medicine (in press).

  12. Hackett, P.B., S.E. Ekker and J.J. Essner (2003). REVIEW: Applications of Transposable Elements in Fish for Transgenesis and Functional Genomics. Fish Development and Genetics (Z. Gong and V. Korzh, eds.) (in press).

  13. Gu, Q., Yang, X., Li, Q., Long, Y., Song, G., Pei, D., Chen, J., Peng, H, Hackett, P.B., and Cui, Z. (2019) Asymmetrical cleavages of Sleeping Beauty transposons generate multiple excised transposon fragments during transposition. bioRxiv 659086; doi: https://doi.org/10.1101/659086. \

  14. Crane AT, Aravalli RN, Asakura A, Carlson D, Cheeran M, Danczyk G, Duttton J, Grande AW, Hackett, PB, Hu WS, Igarashi P, Lu WC, Miller Z, O’Brien T, Panosakaltsis-Mortari A, Parr, AM, Pearce C, Ruiz-Estevez M, Shiao, M, Sipe C, Toman NK, Voth J, Xie H, Steer CJ, Low WC. (2019) Exogenesis of human tissues and organs for transplantation. Cell Transplant. 28: 1091-1105. [PMID:31426664]

  15. Hackett, P.B. (2020). Regulatory issues for genetically modified animals. Front. of Agric. Sci. Eng. 7(2): 188-203. doi.org/10.15302/J-FASE-2019307

  16. Fan Z., My Y., Sonstegard, T., Zhai, X., Li, K., Hackett, P.B., Zhu, Z. (2021).Social acceptance for commercialization of genetically modified food animals. Nat. Sci. Rev. 8(8): nwab067. doi: 10.1093/nsr/nwab067.

  17. Sonstegard TS, Hackett PB. (2021) Infectious disease-resistant pigs: Will they fly? J. Integrat. Agric. 20(1): 1-3. doi: 10.1016/S2095-3119(20)63468-2

  18. Fan Z., Mu Y, Li K, Hackett, PB. (2022). Safety evaluation of genetically modified food animals. Trends Biotechnol. 40(4): 371-373 doi: 10.1016/j.tibtech.2021.10.012