TRAINING FACULTY |
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Name |
Research Short Description |
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Phone |
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We are combining top-down and bottom-up approaches to synthetic biology; we use tools of protein engineering and molecular biology, together with novel synthetic cell technologies, to understand and modulate biological processes in complex systems. |
612-625-9066 |
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Molecular mechanisms of DNA rearrangement/recombination reactions |
aihar001@umn.edu |
612-624-1491 |
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We study the genetics of complex traits: how variation in genome sequences influences individual molecular, cellular and organismal features. We also seek to understand the evolutionary forces that shape genomic diversity. |
falbert@umn.edu |
612-301-1243 |
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*Located on the Duluth campus |
Thyroid Hormone, Brain Development, Blood Brain Barrier, Drug Transport and Metabolism, Lipid Metabolism |
ander163@d.umn.edu |
218-726-6007 |
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*Located on the Duluth campus |
Characterization of genes responsible for the induction and maintenance of hibernation in mammals |
mandrews@d.umn.edu |
218-726-7271 |
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Development and application of state-of-the-art multinuclear, multidimensional magnetic resonance methods to elucidate the structure, dynamics and mechanism of action of biological macromolecules. |
armit001@umn.edu |
612-624-5977 |
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Develops novel techniques that are then used in measurements of subcellular compartments (organelles). The results are useful for evaluating drug drugs as they enter biological cells, monitoring subcellular changes associated with disease or aging, and measuring zeptomole (10-21 mole) amounts. |
arriaga@umn.edu |
612-626-1663 |
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Transcriptional regulation in cancer and development |
bardw001@umn.edu |
612-626-7028 |
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Mechanism of insulin action; regulation of gene expression by lipids, oxidative stress and obesity; adipose biology |
bernl001@umn.edu |
612-624-2712 |
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Regulation of DNA replication, cell cycle, S phase checkpoint, cancer. |
bieli003@umn.edu |
612-624-2469 |
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Developmental mechanisms, neuroscience, and regulation of gene expression |
blaza001@umn.edu |
612-626-2734 |
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Population, evolutionary, and medical genomics; understanding how human genetic variation affects phenotypic diversity and complex disease; computational genomics and metagenomics |
blekhman@umn.edu |
612-624-4092 |
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Physiology and functional genomics of dissimilatory Fe(III)-reducing bacteria; Microbial fuel cells; Engineering of bacteria to interact with electrodes and produce bioproducts |
dbond@umn.edu |
612-624-8619 |
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Discovery of the master regulators of bacterial growth and communication and ultimately, the identification of new antibiotics through the application of diverse tools at the interface of chemistry and biology. |
carlsone@umn.edu |
612-625-2580 |
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Plant Molecular and Cellular Biology |
cjcarter@umn.edu |
612-301-7158 |
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Cell adhesion, signal transduction, cytoskeleton, and C. elegans. |
chenx260@umn.edu |
612-625-1299 |
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Functional proteomics and protein posttranslational modification networks in diseases |
yuechen@umn.edu |
612-626-3340 |
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*Located on the Duluth campus |
Immunoendocrinology, with an emphasis on the role of neuroendocrine peptide hormones as autocrine regulators of immune function |
bclarke@d.umn.edu |
218-726-6587 |
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Yeast and Human Cell Cycle Control |
clark140@umn.edu |
612-624-3442 |
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Clathrin-mediated endocytosis; mammalian intracellular membrane trafficking. |
sdconner@umn.edu |
612-625-3707 |
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*Located on the Duluth campus |
Identification and characterization of susceptibility genes for colorectal cancer including analysis of both human cancer tissues and mouse models of colorectal cancer (CRC) |
rcormier@d.umn.edu |
218-726-8625 |
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Structure, assembly and dynamics of actin-based cytoskeletal network |
ncourtem@umn.edu |
612-624-3195 |
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Nuclear receptors, transcription, gene expression, prostate cancer |
dehm@umn.edu |
612-625-1504 |
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*Located on the Duluth campus |
Molecular characterization of the blood-brain barrier/neurovascular unit with an emphasis on nutrient and drug transport in health and disease. |
ldrewes@d.umn.edu |
218-726-7925 |
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Molecular and cellular mechanisms of regeneration. |
echev020@umn.edu |
612-626-7320 |
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Cellular phosphate uptake and bacterial virulence, chemical bonds to phenotypes, Molecular engineering of enzymes and biotechnological applications |
mhelias@umn.edu |
612-626-1915 |
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The research in the Engelhart laboratory is directed towards better understanding nucleic acid folding and function in order to advance two broad themes: 1) the development of novel nucleic acid-based imaging, analytical, and diagnostic technologies and 2) the elucidation of unanticipated roles for nucleic acids in vivo. |
612-625-1950 |
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Molecular Basis of Muscular Dystrophy; Role of Actin in Cell Polarity |
jervasti@umn.edu |
612-626-6517 |
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Signal transduction and lymphocyte development |
farra005@umn.edu |
612-625-0401 |
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Molecular mechanisms of aging; age-related degenerative diseases and loss of skeletal muscle function; macular degeneration |
ferri013@umn.edu |
612-624-8267 |
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Natural product biosynthesis, Microbial genetics, Targeted metagenomics |
mffreema@umn.edu |
612-624-8575 |
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Cytoskelton and Cell Motility, developmental mechanisms, neuroscience, and regulation of gene expression |
gammi001@umn.edu |
612-625-6158 |
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Chromatin mechanics and dynamics; Quantitative fluorescence microscopy |
klei0091@umn.edu |
612-626-6760 |
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Regenerative medicine, cardiogenesis, and stem-cell biology. |
garry@umn.edu |
612-625-8988 |
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Principles and mechanisms that control expression of genes |
agoldstr@umn.edu |
612-626-7497 |
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How cell surface receptors convert signals from extracellular stimuli like mechanical force into a biological response |
wrgordon@umn.edu |
612-301-1196 |
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Physiology of Shewanella; Geomicrobiology |
gralnick@umn.edu |
612-626-6496 |
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Fundamental and fascinating developmental processes of meiosis and fertilization using C. elegans |
green959@umn.edu |
612-624-3955 |
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The development and application of mass spectrometry-based tools to study proteins and proteomes. |
tgriffin@umn.edu |
612-624-5249 |
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Understand how Rb/E2F1 mediated apoptosis is regulated in normal and cancer cells so it can be manipulated for therapeutic purposes, contributing to impactful and innovative approaches to the treatment of cancer |
halls026@umn.edu |
612-626-2905
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Focuses on the design, synthesis and biophysical characterization of novel small molecules that influence cellular function. |
daharki@umn.edu |
612-625-8687 |
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The causes and consequences of programmed mutagenesis |
rsh@umn.edu |
612-624-0457 |
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Cytoskelton and cell motility, developmental mechanisms |
haysx001@umn.edu |
612-626-2949 |
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Mechanisms of mammalian DNA double-strand break repair |
hendr064@umn.edu |
612-624-5988 |
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*Located on the Duluth campus |
Membrane-localized phenomena |
ahinderl@d.umn.edu |
218-726-7062 |
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Molecular mechanism of cell-fate determination in T cells |
hogqu001@umn.edu |
612-625-1616 |
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Kidney development, transcriptional regulation, microRNAs, primary cilia, polycystic kidney disease (PKD) |
igarashi@umn.edu |
612-625-3654 |
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Development, homeostasis and trafficking of T lymphocytes |
james024@umn.edu |
612-625-1496 |
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Determination of the structural and dynamic basis for the function and assembly of large protein machineries; and the determination of the role of the internal protein dynamics in regulating protein activity and allosteric interactions |
ckalodim@umn.edu |
612-625-1166 |
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Systems biology of plant disease resistance |
katagiri@umn.edu |
612-624-5195 |
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Understanding the molecular and genetic mechanisms of vertebrate limb development and apply the study to elucidate the mechanisms of congenital limb in human and limb regeneration |
kawak005@umn.edu |
612-626-9935 |
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Protein engineering, catalytic promiscuity, enantioselectivity |
rjk@umn.edu |
612-624-5904 |
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Functional genomics, analysis of gene expression patterns, whole genome microarrays |
khodu001@umn.edu |
612-625-3799 |
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Nuclear reprogramming in somatic cell nuclear cloning and stem cells |
kikyo001@umn.edu |
612-624-0498 |
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Biological networks that coordinate metabolism and growth |
dhkim@umn.edu |
612-626-3418 |
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Our computational microbiology lab develops methods that bring precision medicine to the microbiome. We apply those methods to find patterns in microbial communities that predict and diagnose human diseases, and we use those patterns to develop novel therapeutics and diagnostics. |
dknights@umn.edu |
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Cell cycle regulation, Ubiquitination and proteolysis, Genetic mechanisms of tumorigenesis |
koepp015@umn.edu |
612-624-4201 |
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Stem Cell Biology: regulatory pathways, diseases and therapies Transcriptional control of mesoderm development |
kyba@umn.edu |
612-626-5869 |
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Immunity to influenza virus infections |
langlois@umn.edu |
612-625-3633 |
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Identification and understanding of genes involved in cancer development |
larga002@umn.edu |
612-626-4979 |
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How protein-protein interactions induce conformational changes at a distance, a phenomenon termed allostery |
nml@umn.edu |
612-301-1322 |
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Study the structural basis for receptor recognition mechanisms of viruses and for tumor growth and invasion. |
lifang@umn.edu |
612-625-6149 |
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Oxygenases and metalloproteins; magnetic resonance techniques, kinetics |
lipsc001@umn.edu |
612-625-6454 |
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Luxton, G.W. Gant |
Nuclear cell biology; specifically nuclear-cytoskeletal interactions; their formation, regulation and dysfunction in disease |
luxto003@umn.edu |
612-624-8343 |
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Structure-function studies of Lassa fever viral proteins that mediate viral replication and host immune evasion |
hly@umn.edu |
612-625-3358 |
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Focus on signaling and transcriptional mechanisms that regulate osteoclast differentiation |
kmansky@umn.edu |
612-626-5582 |
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Cell and molecular biology of HIV and HTLV |
mansky@umn.edu |
612-626-5525 |
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Characterizing the alterations in metabolism that define diseases such as fatty liver disease and Type 2 Diabetes |
dmashek@umn.edu |
612-626-2904 |
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Structure-based Drug Design and Discovery |
mayox001@umn.edu |
612-625-9968 |
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Gene therapy for genetic disease and cancer using viral and non-viral vectors |
mcivo001@umn.edu |
612-626-1497 |
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Craniofacial muscles in health and disease |
mcloo001@umn.edu |
612-626-0777 |
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Integrative systems biology of cardiovascular function, Cardiac genetic engineering and experimental cardia gene therapy |
metzgerj@umn.edu |
612-625-8296 |
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My lab works on pediatric cancer genetics, immunotherapy, and gene therapy using cutting edge technologies, including DNA transposons, TALENs, and CRISPR/Cas9 |
612-625-2226 |
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Carcinogen and nicotine metabolism by P450 2A enzymes and UDP-glucuronsyl transferases |
murph062@umn.edu |
612-624-7633 |
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Computational biology and functional genomics - Machine learning for integrating diverse genomic data to make inferences about biological networks |
cmyers@cs.umn.edu |
612-624-8306 |
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Molecular and genetic analysis of Drosophila development |
nakat003@umn.edu |
612-625-1727 |
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Developmental control of growth and cell proliferation in Drosophila |
neufe003@umn.edu |
612-625-5158 |
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Cell-cell interactions in growth, differentiation, and development |
moconnor@umn.edu |
612-626-0642 |
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Using chemical biology to develop techniques for measuring protein activities inside living cells. |
llparker@umn.edu |
612-624-9066 |
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Mechanisms controlling lineage decision and reprogramming, and application to regenerative medicine |
perli032@umn.edu |
612-625-4984 |
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Regulation of dynein-based motility |
porte001@umn.edu |
612-626-1901 |
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Signal transduction, natriuretic peptides, guanylyl cyclase receptors and cGMP |
potter@umn.edu |
612-624-7251 |
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Chemical Biology, Environmental chemistry, Inorganic chemistry |
larryque@umn.edu |
612-625-0389 |
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Environmental Microbiology, bioremediation, biodegration, host-microbe-interactions, water microbiology |
sadowsky@umn.edu |
612-624-2706 |
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Our group invents and applies protein engineering technologies to study fundamental functional principles of natural and artificial living systems at a cellular level |
schmida@umn.edu |
612-625-1180 |
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Natural product biosynthesis, evolutionary and rational protein design |
schmi232@umn.edu |
612-625-5782 |
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mRNA Stability; Plant-Pathogen Interactions; Gene Expression |
schot002@umn.edu |
612-624-6275 |
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Biocatalysis, Directed Evolution, Protein Enzymes |
seeliq@umn.edu |
612-626-6281 |
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Lymphocyte and tumor cell adhesion, migration and signal transduction |
shimi002@umn.edu |
612-626-6849 |
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Animal development; control of gene expression; chromatin mechanisms |
simon004@umn.edu |
612-626-5097 |
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Protein acrobatics - Study of protein function via protein engineering; Focus on cell signaling and motor proteins |
sivaraj@umn.edu |
612-301-1537 |
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Natural products discovery in the post-genomics era, Precision engineering of diverse bacterial species |
smanski@umn.edu |
612-624-9752 |
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Cellular mechanisms of maintaining genomic stability; DNA damage response during chromosomal replication |
asobeck@umn.edu |
612-624-1343 |
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My laboratory is interested in understanding the lifecycle of retroviruses and use this information 1) to identify new drug targets for HIV, 2) to develop better vectors for gene therapy and 3) to use these vectors for gene discovery. |
somia001@umn.edu |
612-625-6988 |
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My research focuses mainly on the roles of microRNAs in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), obesity, insulin resistance and liver cancer, with the goal to develop novel therapeutic approaches for these disorders. |
gsong@umn.edu |
612-624-9961 |
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Understanding the genatics of cancer in order to develop individualized, targeted therapies |
star0044@umn.edu |
612-626-6971 |
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Molecular dynamics of muscle contraction and disease, using site-directed spectroscopic probes |
ddt@umn.edu |
612-625-0957 |
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Molecular genetic analysis of unconventional myosin function |
titus004@umn.edu |
612-625-8498 |
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Stem cell gene therapy |
tolar003@umn.edu |
612-626-5501 |
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Chemical carcinogenesis, biological mass spectrometry |
trety001@umn.edu |
612-626-3432 |
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Cancer transgenic mouse models and pharmacogenomics |
vanne001@umn.edu |
612-624-9944 |
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Structure and dynamics of membrane embedded enzymes |
vegli001@umn.edu |
612-625-0758 |
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Plant genome engineering through homologous recombination; Retrotransposable elements and genome organization |
voytas@umn.edu |
612-626-4509 |
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Microbial catabolic enzymology/functional genomics: fundamental biological mechanisms, enzyme evolution and biotechnology |
wacke003@umn.edu |
612-625-3785 |
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*Located on the Duluth campus |
Mechanisms by which foreign chemicals, including drugs and industrial and environmental pollutants, interfere with mitochondrial metabolism and genetics to bring about various metabolic diseases |
kwallace@d.umn.edu |
218-726-8899 |
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Pediatric Genetics and Metabolism |
whitley@umn.edu |
612-625-7422 |
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Structural enzymology; metal icons & organic co-factors; Alzheimer's disease |
wilmo004@umn.edu |
612-624-2406 |
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Cancer gene-therapy and virotherapy |
yamam016@umn.edu |
612-624-9131 |
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Function of RNA-binding proteins and non-coding RNAs in post transcriptional gene regulation mechanisms |
jyong@umn.edu |
612-626-2420 |
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Molecular genetics of sexual differentiation, germ cell development, and testis cancer |
zarko001@umn.edu |
612-625-9450 |
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