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Academic Faculty List

TRAINING FACULTY

Name

Research Short Description

Email

Phone

Adamala, Kate

We are combining top-down and bottom-up approaches to synthetic biology; we use tools of protein engineering and molecular biology, together with novel synthetic cell technologies, to understand and modulate biological processes in complex systems.

kadamala@umn.edu

612-625-9066

Aihara, Hideki

Molecular mechanisms of DNA rearrangement/recombination reactions

aihar001@umn.edu

612-624-1491

Albert, Frank

We study the genetics of complex traits: how variation in genome sequences influences individual molecular, cellular and organismal features. We also seek to understand the evolutionary forces that shape genomic diversity.

falbert@umn.edu

612-301-1243

Anderson, Grant

*Located on the Duluth campus

Thyroid Hormone, Brain Development, Blood Brain Barrier, Drug Transport and Metabolism, Lipid Metabolism

ander163@d.umn.edu

218-726-6007

Andrews, Matthew

*Located on the Duluth campus

Characterization of genes responsible for the induction and maintenance of hibernation in mammals

mandrews@d.umn.edu

218-726-7271

Armitage, Ian

Development and application of state-of-the-art multinuclear, multidimensional magnetic resonance methods to elucidate the structure, dynamics and mechanism of action of biological macromolecules.

armit001@umn.edu 

612-624-5977

Arriaga, Edgar

Develops novel techniques that are then used in measurements of subcellular compartments (organelles). The results are useful for evaluating drug drugs as they enter biological cells, monitoring subcellular changes associated with disease or aging, and measuring zeptomole (10-21 mole) amounts.

arriaga@umn.edu

612-626-1663

Bardwell, Vivian

Transcriptional regulation in cancer and development

bardw001@umn.edu

612-626-7028

Bernlohr, David

Mechanism of insulin action; regulation of gene expression by lipids, oxidative stress and obesity; adipose biology

bernl001@umn.edu

612-624-2712

Bielinsky, Anja-Katrin

Regulation of DNA replication, cell cycle, S phase checkpoint, cancer.

bieli003@umn.edu

612-624-2469

Blazar, Bruce

Developmental mechanisms, neuroscience, and regulation of gene expression

blaza001@umn.edu

612-626-2734

Blekhman, Ran

Population, evolutionary, and medical genomics; understanding how human genetic variation affects phenotypic diversity and complex disease; computational genomics and metagenomics

blekhman@umn.edu

612-624-4092

Bond, Daniel

Physiology and functional genomics of dissimilatory Fe(III)-reducing bacteria; Microbial fuel cells; Engineering of bacteria to interact with electrodes and produce bioproducts

dbond@umn.edu

612-624-8619

Carlson, Erin

Discovery of the master regulators of bacterial growth and communication and ultimately, the identification of new antibiotics through the application of diverse tools at the interface of chemistry and biology. 

carlsone@umn.edu

612-625-2580

Carter, Clay

Plant Molecular and Cellular Biology

cjcarter@umn.edu

612-301-7158

Chen, Lihsia

Cell adhesion, signal transduction, cytoskeleton, and C. elegans.

chenx260@umn.edu

612-625-1299

Chen, Yue

Functional proteomics and protein posttranslational modification networks in diseases

yuechen@umn.edu

612-626-3340

Clarke, Benjamin

*Located on the Duluth campus

Immunoendocrinology, with an emphasis on the role of neuroendocrine peptide hormones as autocrine regulators of immune function

bclarke@d.umn.edu

218-726-6587

Clarke, Duncan

Yeast and Human Cell Cycle Control

clark140@umn.edu

612-624-3442

Conner, Sean

Clathrin-mediated endocytosis; mammalian intracellular membrane trafficking.

sdconner@umn.edu

612-625-3707

Cormier, Robert

*Located on the Duluth campus

Identification and characterization of susceptibility genes for colorectal cancer including analysis of both human cancer tissues and mouse models of colorectal cancer (CRC)

rcormier@d.umn.edu

218-726-8625

Courtemanche, Naomi

Structure, assembly and dynamics of actin-based cytoskeletal network

ncourtem@umn.edu

612-624-3195

Dehm, Scott

Nuclear receptors, transcription, gene expression, prostate cancer

dehm@umn.edu

612-625-1504

Dong, Zigang

Tumor promoter-induced signal transduction pathways and their role in the process of neoplastic cell transformation, carcinogenesis, and cancer prevention

dongx004@umn.edu

507-437-5600

Drewes, Lester

*Located on the Duluth campus

Molecular characterization of the blood-brain barrier/neurovascular unit with an emphasis on nutrient and drug transport in health and disease. 

ldrewes@d.umn.edu

218-726-7925

Echeverri, Karen

Molecular and cellular mechanisms of regeneration. 

echev020@umn.edu

612-626-7320

Elias, Mikael

Cellular phosphate uptake and bacterial virulence, chemical bonds to phenotypes, Molecular engineering of enzymes and biotechnological applications

mhelias@umn.edu

612-626-1915

Engelhart, Aaron

The research in the Engelhart laboratory is directed towards better understanding nucleic acid folding and function in order to advance two broad themes: 1) the development of novel nucleic acid-based imaging, analytical, and diagnostic technologies and 2) the elucidation of unanticipated roles for nucleic acids in vivo.

enge0213@umn.edu

612-625-1950

Ervasti, James

Molecular Basis of Muscular Dystrophy; Role of Actin in Cell Polarity

jervasti@umn.edu

612-626-6517

Farrar, Michael

Signal transduction and lymphocyte development

farra005@umn.edu

612-625-0401

Ferrington, Deborah

Molecular mechanisms of aging; age-related degenerative diseases and loss of skeletal muscle function; macular degeneration 

ferri013@umn.edu

612-624-8267

Freeman, Michael

Natural product biosynthesis, Microbial genetics, Targeted metagenomics

mffreema@umn.edu

612-624-8575

Gammill, Laura

Cytoskelton and Cell Motility, developmental mechanisms, neuroscience, and regulation of gene expression

gammi001@umn.edu

612-625-6158

Gardner, Melissa

Chromatin mechanics and dynamics; Quantitative fluorescence microscopy

klei0091@umn.edu

612-626-6760

Garry, Daniel

Regenerative medicine, cardiogenesis, and stem-cell biology.

garry@umn.edu

612-625-8988

Goldstrohm, Aaron

Principles and mechanisms that control expression of genes

agoldstr@umn.edu

612-626-7497

Gordon, Wendy

How cell surface receptors convert signals from extracellular stimuli like mechanical force into a biological response

wrgordon@umn.edu

612-301-1196

Gralnick, Jeffrey

Physiology of Shewanella; Geomicrobiology

gralnick@umn.edu

612-626-6496

Greenstein, David

Fundamental and fascinating developmental processes of meiosis and fertilization using C. elegans

green959@umn.edu

612-624-3955

Griffin, Timothy

The development and application of mass spectrometry-based tools to study proteins and proteomes.

tgriffin@umn.edu

612-624-5249

Hallstrom, Tim

Understand how Rb/E2F1 mediated apoptosis is regulated in normal and cancer cells so it can be manipulated for therapeutic purposes, contributing to impactful and innovative approaches to the treatment of cancer

halls026@umn.edu

612-626-2905

 

Harki, Daniel

Focuses on the design, synthesis and biophysical characterization of novel small molecules that influence cellular function.

daharki@umn.edu

612-625-8687

Harris, Reuben

The causes and consequences of programmed mutagenesis

rsh@umn.edu

612-624-0457

Hays, Thomas

Cytoskelton and cell motility, developmental mechanisms

haysx001@umn.edu

612-626-2949

Hendrickson, Eric

Mechanisms of mammalian DNA double-strand break repair

hendr064@umn.edu

612-624-5988

Hinderliter, Anne

*Located on the Duluth campus

Membrane-localized phenomena

ahinderl@d.umn.edu

218-726-7062

Hogquist, Kristin

Molecular mechanism of cell-fate determination in T cells

hogqu001@umn.edu

612-625-1616

Igarashi, Peter

Kidney development, transcriptional regulation, microRNAs, primary cilia, polycystic kidney disease (PKD)

igarashi@umn.edu

612-625-3654

Jameson, Stephen

Development, homeostasis and trafficking of T lymphocytes

james024@umn.edu

612-625-1496

Kalodimos, Charalampos

Determination of the structural and dynamic basis for the function and assembly of large protein machineries; and the determination of the role of the internal protein dynamics in regulating protein activity and allosteric interactions

ckalodim@umn.edu

612-625-1166

Katagiri,  Fumiaki

Systems biology of plant disease resistance

katagiri@umn.edu

612-624-5195

Kawakami, Yasuhiko

Understanding the molecular and genetic mechanisms of vertebrate limb development and apply the study to elucidate the mechanisms of congenital limb in human and limb regeneration

kawak005@umn.edu

612-626-9935

Kazlauskas, Romas 

Protein engineering, catalytic promiscuity, enantioselectivity

rjk@umn.edu

612-624-5904

Khodursky, Arkady

Functional genomics, analysis of gene expression patterns, whole genome microarrays

khodu001@umn.edu

612-625-3799

Kikyo, Nobuaki

Nuclear reprogramming in somatic cell nuclear cloning and stem cells

kikyo001@umn.edu

612-624-0498

Kim, Do-Hyung

Biological networks that coordinate metabolism and growth

dhkim@umn.edu

612-626-3418

Knights, Dan

Our computational microbiology lab develops methods that bring precision medicine to the microbiome. We apply those methods to find patterns in microbial communities that predict and diagnose human diseases, and we use those patterns to develop novel therapeutics and diagnostics.

dknights@umn.edu

 

Koepp, Deanna

Cell cycle regulation, Ubiquitination and proteolysis, Genetic mechanisms of tumorigenesis

koepp015@umn.edu

612-624-4201

Kyba, Michael

Stem Cell Biology: regulatory pathways, diseases and therapies Transcriptional control of mesoderm development

kyba@umn.edu

612-626-5869

Langlois, Ryan

Immunity to influenza virus infections

langlois@umn.edu

612-625-3633

Largaespada, David

Identification and understanding of genes involved in cancer development

larga002@umn.edu

612-626-4979

Levinson, Nicholas

How protein-protein interactions induce conformational changes at a distance, a phenomenon termed allostery

nml@umn.edu

612-301-1322

Li, Fang

Study the structural basis for receptor recognition mechanisms of viruses and for tumor growth and invasion.

lifang@umn.edu

612-625-6149

Lipscomb, John

Oxygenases and metalloproteins; magnetic resonance techniques, kinetics

lipsc001@umn.edu

612-625-6454

Luxton, G.W. Gant

Nuclear cell biology; specifically nuclear-cytoskeletal interactions; their formation, regulation and dysfunction in disease

luxto003@umn.edu

612-624-8343

Ly, Hinh

Structure-function studies of Lassa fever viral proteins that mediate viral replication and host immune evasion

hly@umn.edu

612-625-3358

Mansky, Kim

Focus on signaling and transcriptional mechanisms that regulate osteoclast differentiation

kmansky@umn.edu

612-626-5582

Mansky, Lou

Cell and molecular biology of HIV and HTLV

mansky@umn.edu

612-626-5525

Mashek, Douglas

Characterizing the alterations in metabolism that define diseases such as fatty liver disease and Type 2 Diabetes

dmashek@umn.edu

612-626-2904

Mayo, Kevin

Structure-based Drug Design and Discovery

mayox001@umn.edu

612-625-9968

McIvor, R Scott

Gene therapy for genetic disease and cancer using viral and non-viral vectors

mcivo001@umn.edu

612-626-1497

McLoon, Linda

Craniofacial muscles in health and disease

mcloo001@umn.edu

612-626-0777

Metzger, Joseph

Integrative systems biology of cardiovascular function, Cardiac genetic engineering and experimental cardia gene therapy

metzgerj@umn.edu

612-625-8296

Moriarity, Branden

My lab works on pediatric cancer genetics, immunotherapy, and gene therapy using cutting edge technologies, including DNA transposons, TALENs, and CRISPR/Cas9

mori0164@umn.edu

612-625-2226

Murphy, Sharon

Carcinogen and nicotine metabolism by P450 2A enzymes and UDP-glucuronsyl transferases

murph062@umn.edu

612-624-7633

Myers, Chad

Computational biology and functional genomics - Machine learning for integrating diverse genomic data to make inferences about biological networks

cmyers@cs.umn.edu

612-624-8306

Nakato,  Hiroshi

Molecular and genetic analysis of Drosophila development

nakat003@umn.edu

612-625-1727

Neufeld, Thomas

Developmental control of growth and cell proliferation in Drosophila

neufe003@umn.edu

612-625-5158

O'Connor, Michael

Cell-cell interactions in growth, differentiation, and development

moconnor@umn.edu

612-626-0642

Parker, Laurie

Using chemical biology to develop techniques for measuring protein activities inside living cells.

llparker@umn.edu

612-624-9066

Perlingeiro, Rita

Mechanisms controlling lineage decision and reprogramming, and application to regenerative medicine

perli032@umn.edu

612-625-4984

Porter, Mary

Regulation of dynein-based motility

porte001@umn.edu

612-626-1901

Potter,  Lincoln

Signal transduction, natriuretic peptides, guanylyl cyclase receptors and cGMP

potter@umn.edu

612-624-7251

Que, Lawrence

Chemical Biology, Environmental chemistry, Inorganic chemistry

larryque@umn.edu

612-625-0389

Sadowsky, Michael

Environmental Microbiology, bioremediation, biodegration, host-microbe-interactions, water microbiology

sadowsky@umn.edu

612-624-2706

Schmidt, Daniel

Our group invents and applies protein engineering technologies to study fundamental functional principles of natural and artificial living systems at a cellular level

schmida@umn.edu

612-625-1180

Schmidt-Dannert, Claudia 

Natural product biosynthesis, evolutionary and rational protein design

schmi232@umn.edu

612-625-5782

Schottel, Janet

mRNA Stability; Plant-Pathogen Interactions; Gene Expression

schot002@umn.edu

612-624-6275

Seelig, Burckhard

Biocatalysis, Directed Evolution, Protein Enzymes

seeliq@umn.edu

612-626-6281

Shimizu, Yoji

Lymphocyte and tumor cell adhesion, migration and signal transduction

shimi002@umn.edu

612-626-6849

Simon, Jeffrey

Animal development; control of gene expression; chromatin mechanisms

simon004@umn.edu

612-626-5097

Sivaramakrishnan, Sivaraj (Shiv)

Protein acrobatics - Study of protein function via protein engineering; Focus on cell signaling and motor proteins

sivaraj@umn.edu

612-301-1537

Smanski, Michael

Natural products discovery in the post-genomics era, Precision engineering of diverse bacterial species

smanski@umn.edu

612-624-9752

Sobeck, Alexandra

Cellular mechanisms of maintaining genomic stability; DNA damage response during chromosomal replication

asobeck@umn.edu

612-624-1343

Somia, Nikunj

My laboratory is interested in understanding the lifecycle of retroviruses and use this information 1) to identify new drug targets for HIV, 2) to develop better vectors for gene therapy and 3) to use these vectors for gene discovery.

somia001@umn.edu

612-625-6988

Song, Guisheng

My research focuses mainly on the roles of microRNAs in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), obesity, insulin resistance and liver cancer, with the goal to develop novel therapeutic approaches for these disorders.

gsong@umn.edu

612-624-9961

Starr, Tim

Understanding the genatics of cancer in order to develop individualized, targeted therapies

star0044@umn.edu

612-626-6971

Thomas, David

Molecular dynamics of muscle contraction and disease, using site-directed spectroscopic probes

ddt@umn.edu

612-625-0957

Titus, Margaret

Molecular genetic analysis of unconventional myosin function

titus004@umn.edu

612-625-8498

Tolar, Jakub

Stem cell gene therapy

tolar003@umn.edu

612-626-5501

Tretyakova, Natalia

Chemical carcinogenesis, biological mass spectrometry

trety001@umn.edu

612-626-3432

Van Ness, Brian

Cancer transgenic mouse models and pharmacogenomics

vanne001@umn.edu

612-624-9944

Veglia, Gianluigi

Structure and dynamics of membrane embedded enzymes

vegli001@umn.edu

612-625-0758

Voytas, Daniel

Plant genome engineering through homologous recombination; Retrotransposable elements and genome organization

voytas@umn.edu

612-626-4509

Wackett, Lawrence

Microbial catabolic enzymology/functional genomics: fundamental biological mechanisms, enzyme evolution and biotechnology 

wacke003@umn.edu

612-625-3785

Wallace, Kendall

*Located on the Duluth campus

Mechanisms by which foreign chemicals, including drugs and industrial and environmental pollutants, interfere with mitochondrial metabolism and genetics to bring about various metabolic diseases

kwallace@d.umn.edu

218-726-8899

Whitley, Chester

Pediatric Genetics and Metabolism

whitley@umn.edu

612-625-7422

Wilmot, Carrie

Structural enzymology; metal icons & organic co-factors; Alzheimer's disease

wilmo004@umn.edu

612-624-2406

Yamamoto, Masato

Cancer gene-therapy and virotherapy

yamam016@umn.edu

612-624-9131

Yong, Jeongsik

Function of RNA-binding proteins and non-coding RNAs in post transcriptional gene regulation mechanisms

jyong@umn.edu

612-626-2420

Zarkower, David

Molecular genetics of sexual differentiation, germ cell development, and testis cancer

zarko001@umn.edu

612-625-9450