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Schmidt-Dannert Lab

Bioinspired Chemistry and Materials

Cells orchestrate with high efficiency a multitude of enzyme catalyzed chemical reactions that synthesize a tremendous diversity of chemical compounds that is unmatched by synthetic methods. We are interested in exploring and utilizing these biosynthetic machineries to enable the discovery sustainable synthesis of valuable compounds for use as fine chemicals, pharmaceuticals and chemical building blocks. Our lab is developing and studying systems to carry out multi-enzyme biocatalysis in vitro and in recombinant hosts for the synthesis of chemicals. By mixing and matching enzyme with desired catalytic activities identified from different sources, we are designing cascades of enzymatic reactions for the synthesis of compounds of interest.

Intrigued by the spatial organization of biological systems at the nano- to macro scale, we are investigating and eplxoring the principles that govern these process for the bottom-up design and low-cost fabrication of new types biomaterials. We are currently designing genetically programmable and self-assembling protein-based nanoarchitectures for biocatalysis and for the fabriction of novel functional bio(inorganic)-materials with emergent properties.

Several postdoc positions are available:

The Schmidt-Dannert lab has several postdoc positions available to work on US government funded research on creating innovative, protein-based materials with emergent biological properties using synthetic biology approaches. Successful candidates should have completed their PhD within the last 3 years in biochemistry, molecular biology, genetic/microbial engineering, synthetic biology, bioengineering, biocatalysis or related fields. Candidates should have experience in genetic/microbial engineering and/or protein engineering/biochemistry or structural biology. The postions can start in the summer/early fall of 2020.

As per the new regulations for US government funded research (in particular for the DOE and DoD), candidates should be US citizens, permanent residents or from countries that are not on the US sensitive coutnries list  

To apply: Send a cover letter describing your research experience and interest, a CV with publication list and references to Claudia Schmidt-Dannert (

Claudia Schmidt-Dannert

Distinguished McKnight Professor

1479 Gortner Avenue
140 Gortner Laboratory
St. Paul, MN 55108

Office: 612-625-5782 
Fax: 612-625-5780