Ervasti Publications

Patrinostro, X., O’Rourke, A. R., Chamberlain, C. M., Moriarity, B. S., Perrin, B. J., & Ervasti, J. M. (2017). Relative importance of βcyto- and γcyto-actin in primary mouse embryonic fibroblasts. Molecular Biology of the Cell, 28(6), 771–782.

Belanto, J. J., Olthoff, J. T., Mader, T. L., Chamberlain, C. M., Nelson, D. M., McCourt, P. M., Talsness D. M., Gundersen. G. G., Lowe, D. A., & Ervasti, J. M. (2016). Independent variability of microtubule perturbations associated with dystrophinopathy. Human Molecular Genetics.

Talsness, D. M., Belanto, J. J., & Ervasti, J. M. (2015). Disease-proportional proteasomal degradation of missense dystrophins. Proceedings of the National Academy of Sciences of the United States of America, 112(40), 12414–12419.

McCourt, J. L., Rhett, K. K., Jaeger, M. A., Belanto, J. J., Talsness, D. M., & Ervasti, J. M. (2015). In vitro stability of therapeutically relevant, internally truncated dystrophins. Skeletal Muscle, 5, 13.

Belanto, J. J., Mader, T. L., Eckhoff, M. D., Strandjord, D. M., Banks, G. B., Gardner, M. K., Lowe, D. A., & Ervasti, J. M. (2014). Microtubule binding distinguishes dystrophin from utrophin. Proceedings of the National Academy of Sciences of the United States of America, 111(15), 5723–5728.

Perrin, B. J., Strandjord, D. M., Narayanan, P., Henderson, D. M., Johnson, K. R., & Ervasti, J. M. (2013). β-actin and fascin-2 cooperate to maintain stereocilia length. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 33(19), 8114–8121.

Cheever, T. R., Li, B., & Ervasti, J. M. (2012). Restricted Morphological and Behavioral Abnormalities following Ablation of β-Actin in the Brain. PLoS ONE, 7(3), e32970.

Henderson, D. M., Lin, A. Y., Thomas, D. D., & Ervasti, J. M. (2012). The Carboxy-Terminal Third Of Dystrophin Enhances Actin Binding Activity. Journal of Molecular Biology, 416(3), 414–424.

Bunnell, T. M., Burbach, B. J., Shimizu, Y., & Ervasti, J. M. (2011). β-Actin specifically controls cell growth, migration, and the G-actin pool. Molecular Biology of the Cell, 22(21), 4047–4058.

Baltgalvis, K. A., Jaeger, M. A., Fitzsimons, D. P., Thayer, S. A., Lowe, D. A., & Ervasti, J. M. (2011). Transgenic overexpression of γ-cytoplasmic actin protects against eccentric contraction-induced force loss in mdx mice. Skeletal Muscle, 1, 32.

Henderson, D. M., Belanto, J. J., Li, B., Heun-Johnson, H., & Ervasti, J. M. (2011). Internal deletion compromises the stability of dystrophin. Human Molecular Genetics, 20(15), 2955–2963.

Prins, K. W., Call, J. A., Lowe, D. A., & Ervasti, J. M. (2011). Quadriceps myopathy caused by skeletal muscle-specific ablation of βcyto-actin. Journal of Cell Science, 124(6), 951–957.

Bunnell, T.M. and Ervasti, J.M. (2010) Delayed embryonic development and impaired cell growth and survival in Actg1 null mice. Cytoskeleton 67:564-572.

Henderson, D.M., Lee, A. and Ervasti, J.M. (2010) Disease-Causing Missense Mutations in Actin Binding Domain 1 of Dystrophin Induce Thermodynamic Instability and Protein Aggregation. Proc. National Acad. Sci. USA 107:9632-9637.

Perrin, B.J. and Ervasti, J.M. (2010) The actin gene family: function follows isoform. Cytoskeleton (In Press).

Perrin, B.J., Sonnemann, K.J and Ervasti, J.M. (2010) β-actin and γ-actin are each dispensible for auditory hair cell development but required for stereocilia maintenance. PLoS Genetics (In Press).

Belyantseva, I.A., Perrin, B.J., Sonnemann, K.J., Zhu, M., Stepanyan, R., McGee, J., Frolenkov, G.A., Walsh, E.J., Friderici, K.H., Friedman, T.B. and Ervasti, J.M. (2009) γ-Actin is required for cytoskeletal maintenance but not development. Proc. National Acad. Sci. USA 106:9703-9708.

Jaeger, M.A., Sonnemann, K.J., Fitzsimons, D., Prins, K.W. and Ervasti, J.M. (2009) Context dependent functional substitution of α-skeletal actin by γ-cytoplasmic actin FASEB J. 23:2205-2214.

Prins, K.W., Humston, J.M., Mehta, A., Tate, V., Ralston, E. and Ervasti, J.M. (2009) Dystrophin is a microtubule-associated protein J. Cell Biol. 186:363-369.

Prochniewicz, E., Henderson, D.M., Ervasti, J.M. and Thomas, D.D. (2009) Dystrophin and utrophin have distinct effects on the structural dynamics of actin Proc. National Acad. Sci. USA 106:7822-7827.

Sonnemann, K.J., Heun-Johnson, H., Turner A.J., Baltgalvis, K., Lowe D.A. and Ervasti, J.M. (2009) Functional substitution by TAT-utrophin in dystrophin deficient mice. PLoS Med. 6:e1000083.

Bunnell, T.M., Jaeger M.A., Fitzsimons, D.P., Prins, K.W. and Ervasti, J.M. (2008) Destabilization of the dystrophin-glycoprotein complex without functional deficits in α-dystrobrevin null muscle PLoS One 3:e2604.

Ervasti, J.M. and Sonnemann, K.J. (2008) Biology of the Dystrophin-Glycoprotein Complex. In: International Review of Cytology; A Survey of Cell Biology (K.W. Jeon, ed.) Ch. 5, pp. 191-225, Elsevier, San Diego.

Prins K.W., Lowe D.A. and Ervasti, J.M. (2008) Skeletal muscle-specific ablation of γcyto-actin does not exacerbate the mdx phenotype. PLoS One 3:e2419.

Ervasti, J.M. (2007) Dystrophin, its interactions with other proteins, and implications for muscular dystrophy. BBA Molec. Basis Dis. 1772:108-117 (Published online June 7, 2006 DOI 10.1016/j.bbadis.2006.05.010).

Hanft, L.M., Rybakova, I.N., Patel, J.R., Rafael, J.A. and Ervasti, J.M. (2006) Cytoplasmic γ-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle. Proc. National Acad. Sci. USA 103:5385-5390 (Published online March 24, 2006 10.1073/pnas.0600980103).

Rybakova, I.N., Humston, J.L., Sonnemann, K.J. and Ervasti, J.M. (2006) Dystrophin and utrophin bind actin filaments through distinct modes of contact. J. Biol. Chem. 281:9996-10001 (Published online 13 February 2006, 10.1074/jbc.M513121200).

Sonnemann, K.J., Fitzsimons, D.P., Patel, J.R., Liu, Y.W., Schneider, M.F., Moss, R.L. and Ervasti, J.M. (2006) Cytoplasmic γ-actin is not required for skeletal muscle development but its absence leads to a progressive myopathy. Dev. Cell 11:387-397 (Published online September 5, 2006, DOI10.1016/j.devcel.2006.07.001).