August 24, 2017
Succeeding in the social world is a balancing act. On the one hand the opportunity to work together with other genes, individuals, species provides the opportunity to do things differently and more efficiently. On the other hand, such interactions lead parties open to exploitation and deceit. We explore the genomics of conflict across plants, animals and microbes, and explore how such conflicts (and their resolution) can shape genome structure, gene expression, and basic features of life.
For more information about this year's symposium, please click here.
Genomics of Beer
Beyond Genomes: Epigenetic Inheritance
The term 'epigenetic' can be used to describe heritable variation that is not attributable solely to DNA sequence. This can include inheritance of gene expression or chromatin states through mitosis or meiosis. There are classical examples of epigenetics such as imprinting, X-chromosome inactivation, transposable element inactivation and paramutation that violate Mendelian inheritance patterns. Epigenetic regulation of gene expression has been proposed to play broad roles in development, response to environmental cues and natural variation. There is also evidence that transposons are a major target of epigenetic regulation. The speakers for the symposium will highlight diverse phenomena and mechanisms that relate to epigenetic inheritance in several different eukaryotic species.
The Hidden Side of Everything: Contributions of Microbes to Eukaryotic Fitness
The goal of this symposium was to highlight the approaches and ﬁndings from studies of microbes associated with plants and animals.Topics included the analysis of endophytes in plants, the role of bacteria in promoting plant growth, and explore complex symbiotic relationships that bacteria can develop with animals.
Systems Biology of Genetic Regulation
Beyond the reference: Population genomics
The mission of the Microbial and Plant Genomics Institute (MPGI) is to promote advances in microbial and plant genomics, genomics‐enabled science, and molecular genetics for the benefit of society. Our knowledge of genomes is advancing rapidly. While initial efforts often focused on building a reference genome assembly for a particular species, we are now moving towards characterizing the full genomes for many individuals within a species. This is reshaping how we think about the types of variation within a species and how this genomic variation contributes to phenotypic differences. The goal of this symposium is to highlight the approaches and findings of genomic studies of diversity. Topics will include: genome‐wide association studies, genome structure evolution and genomic content variation.
Biological applications of next‐generation sequencing
The mission of the Microbial and Plant Genomics Institute (MPGI) is to promote advances in microbial and plant genomics, genomics‐enabled science, and molecular genetics for the benefit of society. Advances in genomics have already had major impacts on how we address modern scientific questions. This has led to an acceleration of knowledge acquisition and application to biological problems. Recent advances in sequencing technology, the so‐called next‐generation sequencing, have provided opportunities to address biological questions with amazing precision and depth. The focus of this symposium is to observe how high‐throughput sequencing approaches are being applied to biological questions. The one‐day symposia will include presentation from external speakers as well as University of Minnesota researchers. Topics will include evolutionary genomics, metagenomics, comparative genomics, epigenome profiling and additional areas.
Do you have an idea for the next MPGI Symposium?
Share your ideas with MPGI Director Jeff Gralnick at email@example.com