Office Address
6-106 MCB
420 Washington Ave SE
Minneapolis, MN 55455
United States
Lab Address
United States
Lei Zhang
Assistant Professor
Biochemistry, Molecular Biology, and Biophysics
The general interest of the Zhang Laboratory focuses on the genome and epigenome instability in aging and longevity. More specifically we study somatic DNA mutations and epi-mutations and their effects on cellular functional decline in normal aging process or age-related diseases. We have been developing experimental approaches of single-cell multi-omics and applying them to discover interactions of genome, transcriptome and epigenome in individual cells from different tissues of humans during aging or species with different maximum life spans.
Education and background
Dr. Zhang obtained her PhD in microbiology in the Shanghai Institutes of Biological Sciences at the Chinese Academy of Sciences in 2014. She completed postdoc training in the Department of Genetics at the Albert Einstein College of Medicine in 2021. After that, she joined the Xiao Dong laboratory as a Research Assistant Professor. Since 2023, she started the Lei Zhang laboratory in the Institute on the Biology of Aging and Metabolism (iBAM) and the Department of Biochemistry, Molecular Biology and Biophysics (BMBB) at the University of Minnesota, Twin Cities.