News release: In preventing nuclear collapse in cells, scientists inch closer to a treatment for a set of rare diseases

December 02, 2020


Nuclear collapse

University of Minnesota researchers have discovered a potential target for the research and development of future therapies to mitigate the symptoms of a series of genetic disorders called laminopathies. Laminopathies cause a wide variety of conditions in humans, from skeletal muscular dystrophy and neuropathy to premature aging.

In a study published in the Proceedings of the National Academy of Sciences (PNAS), researchers set out to better understand how mutations in proteins that associate with the nuclear envelope — which encases each cell’s nucleus — cause laminopathies. Read more