Office Address
420 Washington Avenue SE
Minneapolis, MN 55455
United States
Aaron Goldstrohm
Department Head, Professor
Biochemistry, Molecular Biology, and Biophysics
We seek to discover the mechanisms that control translation, stability, and localization of mRNAs and to identify the networks of genes that are coordinately regulated by RNA-binding proteins and ribonucleases. Our discoveries are broadly relevant, with particular importance to stem cell and developmental biology. The results of our work will promote development of therapeutic approaches to correct deleterious gene expression in cancer and neurological diseases.
Mission statement
The goal of my research is to discover how genes are properly switched on or off during the development of an animal, including humans. Our research benefits society by improving our understanding of normal biological processes. This information also helps determine how errors in the control of genes can cause human diseases. The genes that we study affect several human diseases, including cancer, neurodegeneration, epilepsy, and the movement disorder ataxia. Our discoveries will promote development of therapeutic strategies to correct errors in genes.
Of equal importance, I strive to educate the next generation of scientists and healthcare professionals.
Research statement
We seek to discover the mechanisms that control translation, stability, and localization of mRNAs and to identify the networks of genes that are coordinately regulated by RNA-binding proteins and ribonucleases. Our discoveries are broadly relevant, with particular importance to stem cell and developmental biology. The results of our work will promote development of therapeutic approaches to correct deleterious gene expression in cancer and neurological diseases.