Gardner Lab: Publications

Papers in reverse chronological order

Mooneyham A, Iizuka Y, Yang Q, Coombes C, McClellan M, Shridhar V, Emmings E, Shetty M, Chen L, Ai T, Meints J, Lee MK, Gardner MK, Bazzaro M.; UNC-45A is a Novel Microtubule associated Protein and Regulator of Paclitaxel Sensitivity in Ovarian Cancer Cells. Molecular Cancer Research : MCR. 2018

Reid TA, Coombes C, Gardner MK.; Manipulation and quantification of microtubule lattice integrity., Biology Open 2017 2017; 6(8):1245-1256. Download PDF

Gardner, MK.; Cell Biology: Microtubule Collisions to the Rescue. Current Biology : CB. 2016; 26(24):R1287-R1289

Coombes C, Yamamoto A, McClellan M, Reid TA, Plooster M, Luxton GW, Alper J, Howard J, Gardner MK.; Mechanism of microtubule lumen entry for the α-tubulin acetyltransferase enzyme αTAT1., Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7176-E7184. Download PDF

Erickson J, Gearhart M, Honson D, Reid T, Gardner M, Moriarity B, and Echeverri, K.. A novel role for SALL4 during scar-free wound healing in axolotl. npj Regenerative Medicine. 2016 December 08; 1:16016.  

Stern LA, Schrack IA, Johnson SM, Deshpande A, Bennett NR, Harasymiw LA, Gardner MK, Hackel BJ., Geometry and expression enhance enrichment of functional yeast-displayed ligands via cell panning., Biotechnology and bioengineering. 2016; 113(11):2328-41.   

Edgerton H, Johansson M, Keifenheim D, Mukherjee S, Chacón JM, Bachant J, Gardner MK, Clarke DJ., A noncatalytic function of the topoisomerase II CTD in Aurora B recruitment to inner centromeres during mitosis., The Journal of cell biology. 2016; 213(6):651-64. 8.

TA Reid, BM Schuster, BJ Mann, SK Balchand, M Plooster, M McClellan, CE Coombes, P Wadsworth, and MK Gardner, Suppression of Microtubule Assembly Kinetics by the Mitotic Protein TPX2,  J Cell Sci. 2016 Apr 1;129(7):1319-28. Download PDF

EO Albericoa, ZC Zhua, OY Wua, MK Gardner, DR Kovac and HV Goodson, Interactions between the microtubule binding protein EB1 and F-actin, J Mol Biol. 2016 Mar 27;428(6):1304-1314

C Mauvezin, AL Neisch, CI Ayala, J Kim, A Beltrame, CR Braden, MK Gardner, TS Hays, TP Neufeld, Coordination of autophagosome-lysosome fusion and transport by a Klp98A-Rab14 complex, J Cell Sci. 2016 Mar 1;129(5):971-82.

Hepperla, A.J., Willey, P.T., Coombes, C.E., Schuster, B.M., Gerami-Nejad, M., McClellan, M., Mukherjee, S., Meehl, J., Winey, M., Odde, D.J., O’Toole, E.T., and Gardner, M.K., “Minus-End Directed Kinesin-14 Motors Align Anti-Parallel Microtubules to Control Metaphase Spindle Length”, Developmental Cell;  Oct 13; 31(1):61-72 (2014). Download PDF

Chacón, J.M., Mukherjee, S., Schuster, B.M., Clarke, D.J., and Gardner, M.K, “Pericentromere Tension is Self-Regulated by Spindle Structure in Metaphase”, Journal of Cell Biology; May 12;205(3):313-24 (2014). Download PDF

Belanto, J.J., Mader, T.L., Eckhoff, M.D., Strandjord, D.M., Banks, G.B., Gardner M.K., Lowe, D.A., and Ervasti, J.M., "Microtubule Binding Distinguishes Dystrophin from Utrophin", Proc Natl Acad Sci; Apr15;111(15):5723-8 (2014).

Prahl, L.S., Castle, B.T., Gardner, M.K., and Odde, D.J., "Quantitative Analysis of Microtubule Self-Assembly Kinetics and Tip Structure", Methods Enzymol; 540:35-52 (2014).

Chacón, J.M. and Gardner, M.K, “Analysis and Modeling of Chromosome Congression During Mitosis in the Chemotherapy Drug Cisplatin”, Cellular and Molecular Bioengineering; 6(4): 406-17(2013). Download PDF

Gardner, M.K., “CENP-E Hangs on at dynamic microtubule ends”, Nat Cell Biol; 15(9):1030-2: (2013). Download PDF

Burrack, L.S., Applen-Clancey, S.E., Chacón, J.M., Gardner, M.K., and J. Berman, “Monopolin recruits condensin to organize centromere DNA and repetitive DNA sequences”, Mol Biol Cell; 24(18):2807-19 (2013). Download PDF

Coombes, C.E., Yamamoto A., Kenzie, M.R., Odde, D.J., Gardner M.K., “Evolving tip structures can explain age-dependent microtubule catastrophe”, Curr Biol. Jul 22; 23(14):1342-8 (2013). Download PDF

Choy, J.S., O'Toole, E., Schuster, B.M., Crisp,  M.J., Karpova, T.S., McNally, J.G., Winey, M., Gardner M.K*., and M.A. Basrai*, “Genome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability”, Mol Biol Cell. 24(17):2753-63 (2013). Download PDF

Gardner, M.K., Zanic, M., and J. Howard, “Microtubule Catastrophe and Rescue”, Current Opinion in Cell Biology, 25(1):14-222. (2013) Download PDF

Hendricks AG, Lazarus JE, Perlson E, Gardner MK, Odde DJ, Goldman YE, Holzbaur EL. “Dynein tethers and stabilizes dynamic microtubule plus ends”, Curr Biol Apr 10;22(7):632-7 (2012) Download PDF

Tropini C, Roth EA, Zanic M, Gardner MK, Howard J,  “Islands containing slowly hydrolyzable GTP analogs promote microtubule rescues,” PLoS One; 7(1) (2012). Download PDF

Gardner, M.K., Zanic, M., Gell, C., Bormuth, V., and J. Howard, “Depolymerizing Kinesins Kip3 and MCAK Shape Cellular Microtubule Architecture by Differential Control of Catastrophe”, Cell 147(5):1092-103  (2011) Download PDF

Gardner, M.K., Charlebois, B.D., Janosi, I.M., Howard, J., Hunt, A.J., and D.J. Odde, “Rapid Microtubule Self-assembly Kinetics”, Cell 146(4):1247-60. (2011) Download PDF

Weaver, L.N., Ems-McClung, S.C.,…Gardner, M.K. and C.E. Walczak, “Kif18A Uses a Microtubule Binding Site in the Tail for Plus-End Localization and Spindle Length Regulation”, Current Biology 21(17):1500-6. (2011)  Download PDF

Demchouk, A.O., Gardner, M.K., D.J. Odde, “Microtubule Tip Tracking and Tip Structures at the Nanometer Scale Using Digital Fluorescence Microscopy”, Cellular and Molecular Bioengineering (2011) Download PDF

Havens, K.A., Gardner, M.K., Kamieniecki, R.J., Dresser, M.E., and Dawson, D.S., “Slk19p of Saccharomyces cerevisiae regulates anaphase spindle dynamics through two independent mechanisms”,  Genetics  186(4):1247-60 (2010) Download PDF

Gardner, M.K., Bouck, D., Paliulis, L., Meehl, J., O’Toole, E., Haase, J., Joglekar, A., Winey, M., Salmon, E.D., Bloom, K., and D.J. Odde, “Chromosome congression by kinesin-5 motor-mediated disassembly of longer kinetochore microtubules”, Cell  135: 894-906 (2008) Download PDF

Gardner, M.K., Sprague, B., Pearson, C., Cosgrove, B., Bicek, A., Bloom, K., Salmon, E.D., “Model-Convolution: A computational approach to digital image interpretation”, Cellular and Molecular Bioengineering 3(2):163-170.(2010) Download PDF

Gardner, M.K.and D.J. Odde, “Stochastic simulation and graphic visualization of mitotic processes”, METHODS 51(2):251-6 (2010) Download PDF

Gardner, M.K., Odde, D.J. and K. Bloom, “Kinesin-8 molecular motors: putting the brakes on chromosome oscillations”, Trends in Cell Biology 18(7):307-10. (2008) Download PDF

Gardner, M.K. and D.J. Odde, “Dam1 complexes go it alone on disassembling microtubules”, Nature Cell Biology, 10(4):379-81 (2008) Download PDF

Gardner, M.K., Molk, J., Mythreye, K., Haase, J., Anderson, M., O’Toole, E., Joglekar, A., Winey, M., Odde, D., Salmon, E.D., and K. Bloom, “The microtubule-based motor Kar3 and plus-end binding protein Bim1 provide structural support for the anaphase spindle”, The Journal of Cell Biology, 180(1):91-100 (2008) Download PDF

Gardner, M.K.,Hunt, A.J., Goodson, H.V., and D.J. Odde, “Microtubule assembly dynamics: new insights at the nanoscale”, Current Opinion in Cell Biology, 20(1):64-70 (2008) Download PDF

Schek, H.T*., Gardner, M.K.*, Cheng, J., Odde, D.J., and A.J. Hunt, “ Microtubule assembly dynamics at the nanoscale”, Current Biology, 17(17):1445-55 (2007) Download PDF

Gardner M.K., D. J. Odde, and K. Bloom, “Hypothesis testing via integrated computer modeling and digital fluorescence microscopy,” METHODS, 41(2): 232-7 (2007) Download PDF

Gardner, M.K. and D.J. Odde, “Asymmetric division: motor persistence pays off”, Current Biology, 16(24), R1021-3 (2006) Download PDF

Gardner, M.K. and D.J. Odde, “Modeling of chromosome motility during mitosis”, Current Opinion in Cell Biology, 18(6), 639-47 (2006) Download PDF

Shimogawa M, B Grackzyk, M.K. Gardner, S Francis, E White, M Ess, J Molk, C Ruse, S Niessen, J Yates, E Muller, K Bloom, D.J. Odde, and T.N. Davis, “Mps1 phosphorylation of the kinetochore component Dam1 couples kinetochores to microtubule plus-ends at metaphase,” Current Biology, 16(15), 1489-501 (2006) Download PDF

Pearson, C.G*, M.K. Gardner*, L Paliulis, E.D. Salmon, D.J. Odde, and K. Bloom, “Measuring nanometer scale gradients in spindle microtubule dynamics using model convolution microscopy,” Molecular Biology of the Cell, 17(9), 4069-79, (2006) Download PDF

Gardner, M.K., C. Pearson, B. Sprague, T. Zarzar, K. Bloom, E.D. Salmon, and D.J. Odde, “Tension-dependent regulation of microtubule dynamics at kinetochores can explain metaphase congression in yeast,” Molecular Biology of the Cell, 16, 3764-3775 (2005) Download PDF

Pearson, C.G., E. Yeh, M.K. Gardner, D.J. Odde, E.D. Salmon, and K. Bloom, “Stable kinetochore–microtubule attachment constrains centromere positioning in metaphase,” Current Biology, 14, 1962-1967 (2004) Download PDF


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