For a complete list PubMed publications, click HERE
- Isioma Enwerem*, Nathan Elrod, Chung-Te Chang, Ai Lin, Ping Ji, Jennifer Bohn*, Yevgen Levdansky, Eric Wagner, Eugene Valkov, Aaron Goldstrohm. Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome. RNA Journal. 2021. 27: 445-464. PMID: 33397688
- Elizabeth Abshire*, Kelsey Hughes*, Rucheng Diao, Sarah Pearce, Shreekara Gopalakrishna, Raymond Trievel, Joanna Rorbach, Peter Freddolino, Aaron Goldstrohm. Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide adenine dinucleotide metabolites. Journal of Biological Chemistry. 2020. 295(44): 15112-1513 PMID: 32839274
- Robert Connacher* and Aaron Goldstrohm. Molecular and biological functions of TRIM-NHL RNA-binding proteins. WIRES RNA. 2020, Aug 1. PMID: 32738036
- Michael Wolfe, Trista Schagat*, Michelle Paulsen, Brian Magnuson, Mats Ljungman, Daeyoon Park*, Chi Zhang, Zachary Campbell, Aaron Goldstrohm, Peter Freddolino. Principles of mRNA control by human PUM proteins elucidated from multi-modal experiments and integrative data analysis. 2020. RNA Journal. 26(11):1680-1703. PMCID: PMC7566576
- Rene Arvola*, Joseph Buytendorp*, Chung-te Chang, Yevgen Levdansky, Eugene Valkov, Peter Freddolino, and Aaron Goldstrohm. Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs. Nucleic Acids Research. 2020. 48(4):1843-1871. PMCID: PMC7038932
- Michael Kearse*, Daniel Goldman, Jiou Choi, Chike Nwaezeapu, Dongming Liang, Katelyn Green, Aaron Goldstrohm, Peter Todd, Rachel Green, Jeremy Wilusz. Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. Genes and Development. 2019. 33:1–15. PMID: 31171704
- Michael Wolfe, Aaron Goldstrohm#, and Peter Freddolino#. Global analysis of RNA metabolism using bio-orthogonal labeling coupled with next-generation RNA sequencing. Methods. 2019. Volume 155, Pages 88-103. PMID: 30529548
- Eric Wagner and Aaron Goldstrohm. Biochemical and Next Generation Sequencing Approaches to Study RNA Regulation, Methods. 2019. 155:15. p1-2. PMID: 30797262
- Chen Qiu, Aaron Goldstrohm, and Traci Tanaka Hall. Preparation of cooperative RNA recognition complexes for crystallographic structural studies. Methods Enzymol. 2019;623:1-22. PMID: 31239042
- Wi Lai, Rene Arvola*, Aaron Goldstrohm, and Perry Blackshear. Inhibiting transcription in cultured metazoan cells with actinomycin D to monitor mRNA turnover. Methods. 2019. Volume 155, Pages 77-87. PMID: 30625384
- Aaron Goldstrohm, Traci Tanaka Hall, and Katherine McKenney* Post-transcriptional Regulatory Functions of Mammalian Pumilio Proteins. Trends in Genetics, 2018 Dec;34(12):972-990. PMID: 30316580
- Kelsey Hughes*, Elizabeth Abshire,* and Aaron Goldstrohm. Regulatory Roles of Vertebrate Nocturnin: Insights and Remaining Mysteries. RNA Biology, 2018. 15(10):1255-1267. PMID: 30257600
- Elizabeth Abshire*, Jennifer Chasseur, Jennifer Bohn*, Paul Del Rizzo*, Peter Freddolino, Aaron Goldstrohm#, and Raymond Trievel#. The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells. Nucleic Acids Research. 2018. 46(12): 6257-6270. PMID: 29860338
- Jennifer Bohn*, Jamie Van Etten*, Trista Schagat, Brittany Bowman*, Richard McEachin, Peter Freddolino and Aaron Goldstrohm. Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins. Nucleic Acids Research. 2018. 46(1): 362-386. PMID: 29165587
- Katelyn Green, Rebecca Glineburg, Michael Kearse*, Brittany Flores, Alexander Linsalata, Stephen Fedak, Aaron Goldstrohm, Sami Barmada, and Peter Todd. RAN translation at C9orf72-ALS-associated repeat expansions is selectively enhanced by the integrated stress response. Nature Communications. 2017, Dec 8;8(1):2005. PMID: 29222490
- René Arvola*, Chase Weidmann*, Traci Tanaka Hall, and Aaron Goldstrohm. Combinatorial Control of Messenger RNAs by Pumilio, Nanos and Brain Tumor Proteins. RNA Biology. 2017. Mar 20:1-12. PMID: 28318367
- Tzu-Fang Lou, Chase Weidmann*, Jordan Killingsworth*, Traci Hall, Aaron Goldstrohm, and Zachary Campbell. Integrated analysis of RNA-binding protein complexes using in vitro selection and high-throughput sequencing and sequence specificity landscapes (SEQRS). Methods. 2017. Volumes 118–119, 15 April 2017, Pages 171-181. PMID: 27729296.
- Chase Weidmann*, Chen Qiu, René Arvola*, Tzu-Fang Lou, Jordan Killingsworth*, Zachary Campbell, Traci Hall and Aaron Goldstrohm. Drosophila Nanos acts as a molecular clamp to modulate RNA-binding and repression activities of Pumilio. eLife. 2016. 5, e17096. PMID: 27482653.
- Michael Kearse*, Katelyn Green, Amy Krans, Caitlin Rodriguez, Alexander Linsalata, Aaron Goldstrohm and Peter Todd. CGG Repeat-Associated Non-AUG Translation Utilizes a Cap-Dependent Scanning Mechanism of Initiation to Produce Toxic Proteins. Molecular Cell. 2016. 62(2):314-22. PMID: 27041225
- Chase Weidmann*, Nathan Raynard*, Nathan Blewett*, Jamie Van Etten*, Aaron Goldstrohm. The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation. RNA. 2014. 20:1298-1319. PMID: 24942623
- Joel Hrit*, Nathan Raynard*, Jamie Van Etten*, Kamya Sankar*, Adam Petterson*, and Aaron Goldstrohm. In Vitro Analysis of RNA Degradation Catalyzed by Deadenylase Enzymes. Methods in Molecular Biology. 2014. 1125:325-39. PMID: 24590800
- Jamie Van Etten*, Trista Schagat, and Aaron Goldstrohm. A Guide to Design and Optimization of Reporter Assays for 3’ Untranslated Region Mediated Regulation of Mammalian Messenger RNAs. Methods. 2013. 63:110–118. PMID: 23643865
- Jamie van Etten*, Trista Schagat, Joel Hrit*, Chase Weidmann* and Aaron Goldstrohm. Human Pumilio proteins recruit the Ccr4-Not deadenylase to efficiently repress mRNAs. The Journal of Biological Chemistry. 2012. 287:36370-36383. PMID: 23643865
- Nathan Blewett* and Aaron Goldstrohm. An eIF4E binding protein promotes mRNA decapping and is required for PUF repression. Molecular and Cellular Biology. 2012. 32: 4181-4194. PMID: 22890846
- Chase Weidmann* and Aaron Goldstrohm. Drosophila Pumilio protein contains multiple autonomous repression domains that regulate mRNAs independently of Nanos and Brain Tumor. Molecular and Cellular Biology. 2012. 32:527-540. PMID: 22064486
- Nathan Blewett*, Jeff Coller and Aaron Goldstrohm. A quantitative assay for measuring mRNA decapping by splinted ligation reverse transcription polymerase chain reaction: qSL-RT-PCR. RNA. 2011. 17:535-543. PMID: 21220548
- Nayoung Suh, Sarah L. Crittenden, Aaron Goldstrohm, Brad Hook, Beth Thompson, Marvin Wickens and Judith Kimble. FBF and its control of gld-1 expression in the C. elegans germline. Genetics. 2009. 181(4):1249-60. PMID: 19221201
- Aaron Goldstrohm, Brad Hook and Marvin Wickens. Regulated deadenylation in vitro. Methods in Enzymology. 2008. 448:77-106. PMID: 19111172
- Aaron Goldstrohm and Marvin Wickens. Multifunctional deadenylase complexes diversify mRNA control. Nature Reviews Molecular Cell Biology. 2008. 9, 337-344. PMID: 18334997
- Aaron Goldstrohm, Daniel Seay, Brad Hook, and Marvin Wickens. PUF protein mediated deadenylation is catalyzed by Ccr4p. Journal of Biological Chemistry. 2007. 228, 109-114. PMID: 17090538
- Brad Hook, Aaron Goldstrohm, Daniel Seay, and Marvin Wickens. Two yeast PUF proteins negatively regulate a single mRNA. Journal of Biological Chemistry. 2007. 282, 15430-15438. PMID: 17389596
- Miguel Sánchez Alvarez1, Aaron Goldstrohm1, Mariano Garcia-Blanco, and Carlos Suñé. The human transcription elongation factor CA150 localizes to splicing factor-rich nuclear speckles and assembles transcription and splicing components into complexes through its amino and carboxyl regions. Molecular and Cellular Biology. 2006. 26, 4998-5014. PMID: 16782886
- Aaron Goldstrohm, Brad Hook, Daniel Seay, and Marvin Wickens. PUF proteins bind Pop2p to regulate mRNAs. Nature Structural and Molecular Biology. 2006. 13, 533-539. PMID: 16715093
- Marvin Wickens and Aaron Goldstrohm. A Place to Die, a Place to Sleep. Science. 2003. 300, 753-755.
- Aaron Goldstrohm, Arno Greenleaf, and Mariano Garcia-Blanco. Co-transcriptional Splicing of Pre-messenger RNAs: Considerations for the Mechanism of Alternative Splicing. Gene. 2001. 277, 31-47. PMID: 11602343
- Aaron Goldstrohm, Todd Albrecht, Carlos Suñé, Mark Bedford, and Mariano Garcia-Blanco. The human transcription elongation factor CA150 interacts with RNA Polymerase II and the pre-mRNA splicing factor SF1. Molecular and Cellular Biology. 2001. 21, 7617-7628. PMID: 11604498
- Carlos Suñé1, Aaron Goldstrohm1, Junmin Peng, David Price, and Mariano Garcia-Blanco.An in vitro transcription system that recapitulates EIAV Tat-mediated inhibition of HIV-1 Tat activity demonstrates a role for P-TEFb and associated proteins in the mechanism of Tat activation. Virology. 2000. 274, 356-366. PMID: 10964778
- Sherry Carty, Aaron Goldstrohm, Carlos Suñé, Mariano Garcia-Blanco, and Arno Greenleaf. Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphor-CTD of RNA polymerase II. Proceedings of the National Academy of Sciences. 2000. 97, 9015-902. PMID: 10908677
Career and Professional Development Articles
- Albert Chen, Sara Wong, Gabriel Martinez-Santibanez, Angelina Londono-Joshi, Paula Wishart, Aaron Goldstrohm. Cold E-mails and Hot Coffee: Take action on your career. Science Careers, June 18, 2015.
- Albert Chen, Sara Wong, Gabriel Martinez-Santibanez, Angelina Londono-Joshi, Paula Wishart, Aaron Goldstrohm. Cold E-mails and Hot Coffee: Offer Value to Build Your Network From Zero. Science Careers, June 26, 2015
- Sara Wong, Albert Chen, Gabriel Martinez-Santibanez, Angelina Londono-Joshi, Paula Wishart, Aaron Goldstrohm. Cold E-mails and Hot Coffee: Build Skills with the Informational Interview. Science Careers, July 2, 2015
- Gabriel Martinez-Santibanez, Albert Chen, Sara Wong, Angelina Londono-Joshi, Paula Wishart, Aaron Goldstrohm. Cold E-mails and Hot Coffee: Skill Building and Implementation on Campus. Science Careers, July 15, 2015
Books and Chapters in Books
Post-transcriptional Mechanisms in Endocrine Regulation. 2016.
- Editors: K.M.J. Menon and Aaron Goldstrohm.
- Springer International Publishing, Switzerland. p341. ISBN 978-3-319-25124-0
- Aaron Goldstrohm and K.M.J. Menon.
- Preface. pages: i-viii.
- Rene Arvola*, Elizabeth Abshire*, Jennifer Bohn,* and Aaron Goldstrohm.
- Chapter 1. Mechanisms of Post-transcriptional gene regulation.
- 2016. pages 1-36.
Molecular Biology of Hemoglobin Switching. 1995.
- Editor: G. Stamatoyannopoulos, G. p. 426. Intercept Ltd., Andover, UK.
- Hardison, R., L. Elnitski, A. ElSherbini, Aaron Goldstrohm, J. Jackson, J. Peck, C. Riemer, S. Schwartz, N. Stojanovic, and W. Miller.
- The globin gene server: an aid to studying the regulation of mammalian globin gene clusters. 1995. pages 405-426