Background
Nelson D. Goldberg received his B.Sci. in 1953 from the University of Toledo and following military service at Walter Reed Army Institute of Research, a Ph.D. in 1962 from the University of Wisconsin. He conducted postdoctoral studies with Oliver Lowry at Washington University School of Medicine and moved to the University of Minnesota in 1964 as an Instructor in Pharmacology. He moved quickly through the academic ranks, becoming Professor of Pharmacology in 1972 and Professor of Biochemistry in 1987. His energy and enthusiasm for science were evidenced through his diverse research interests in the area of signal transduction and metabolic control.
During his 40+ year career, he studied TCA-cycle intermediates in the brain, effects of insulin on cyclic nucleotide metabolism in the muscle, and hormonal control of glycogen turnover in the liver. Perhaps his most noteworthy studies were on the synthesis and metabolism of cGMP and its relationship to cAMP mediated signaling events. He demonstrated regulated synthesis of cGMP in response to cholinergic stimulation and developed analytical methods to measure not only the synthesis of phosphorylated molecules, but also their degradation. His interest in "high-energy" phosphoryl compounds continued into the 1990's as he studied the role of adenylate kinase in phosphoryl transfer reactions.
2027 Lecture
Dr. Roland Dunbrack
Fox Chase Cancer Center
Philadelphia, PA
Wednesday, February 3, 2027
10:00 a.m. – 11:00 a.m.
Room TBA
Talk Title TBA
Past Lectures
| Year | Speaker/Affiliation | Title |
|---|---|---|
| 2026 | Dr. Richard J. Youle National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland | Mitochondria, autophagy and inflammation in relation to Parkinson's Disease |
| 2024 | Dr. Jared Rutter University of Utah School of Medicine, Salt Lake City, UT | Metabolism, Cellular Decisions and the Language that Unites Them |
| 2023 | Dr. Evan D. Rosen Harvard Medical School, Boston, MA | Adventures in Adipose Biology |
| 2021 | Dr. Mitchell Lazar Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA | Nuclear Receptors and Metabolism in the 4th Dimension |
| 2019 | Dr. Melanie Cobb University of Texas Southwestern Medical Center, Dallas, TX | Catching a few good WNKs |
| 2018 | Dr. Ron Kopito Stanford University, Stanford, CA | Making the right choice: client specificity in ER protein quality control |
| 2017 | Dr. Rosalind A. Coleman University of North Carolina, Chapel Hill, NC | Lipid Regulation of β-adrenergic Receptor Signaling |
| 2016 | Dr. Alan Saltiel University of California, San Diago, CA | Inflammatory Links Between Obesity and Type 2 Diabetes |
| 2015 | Dr. Karen Reue University of California, Los Angeles, CA | Lipins, autophagy, and metabolic disease |
| 2014 | Dr. Michael Marletta The Scripps Research Institute, La Jolla, CA | Gas Sensing: From Bugs to Humans |
| 2013 | Dr. Sheila Collins Sanford Burnham Medical Research Institute, Orlando, FL | Converging Cyclic Nucleotide Second Messengers Regulate Fat Metabolism |
| 2012 | Dr. Jackie Corbin Vanderbilt University Medical Center, Nashville, TN | Exploring Cyclic Nucleotide Action: Cyclic GMP, Penile Erection, & Viagra |
2011 | Dr. Pere Puigserver Harvard Medical School, Boston, MA | Signaling Control of Mitochondrial Bioenergetics Through the PGC1 Pathway |
2010 | Dr. Joseph Beavo University of Washington, Seattle, WA | New roles for new and old phosphodiesterases |
2009 | Dr. Peter Roach Indiana University School of Medicine, Indianapolis, IN | Glycogen, and Old New Trick? From Multisite Protein in Phosphorylation to Glycogen Phosphorylation to Lafora Disease |
2008 | Dr. Christin Carter-Su University of Michigan Medical School, Ann Arbor, MI | The Role of the Tryosine Kinase JAK2 in Actions of Growth Hormone |
2007 | Dr. George Thomas University of Cincinnati, Cincinnati | Nutrient Sensing in the mTOR/S6K1 Signaling Pathway |
2006 | Dr. Christopher B. Newgard Duke University, Durham | Comprehensive Metabolic Analysis to Identify Mechanisms of Diabetes and Obesity |
2005 | Dr. Barbara B. Kahn Harvard Medical School, Boston | AMP-Activated Protein Kinase: Ancient Fuel Gauge is a Key to Modern Understanding of Metabolism |
2004 | Dr. Morris J. Birnbaum University of Pennsylvania | The Coordinated Control of Growth and Metabolism |
2003 | Dr. M. Daniel Lane Johns Hopkins School of Medicine | The Malonyl-CoA Hypothesis and Regulation of Energy Metabolism |
2002 | Dr. G. Stanley McKnight University of Washington, Seattle | Physiological Functions of Protein Kinase A |
2001 | Dr. Tony Hunter The Salk Institute, La Jolla | Cellular Regulation by Phosphorylation and Ubiquitination |
2000 | Dr. David Garbers UT Southwestern Medical Center, Dallas |